New Phytologist, Volume 250, Issue 2, Page 799-804, April 2026.Summary Plant immunity is complex, and studies of leaf epidermal cells attacked by powdery mildew fungi have been instrumental in revealing how it relies on plant endomembrane trafficking. Immunity against these biotrophic fungi is manifested as cell wall deposits (‘papillae’) and the hypersensitive reaction (HR), both involving plant endomembrane ...
Hans Thordal‐Christensen +3 more
wiley +1 more source
M-Ras distinct activation scenarios: A mechanistic outlook and targeting. [PDF]
Comput Struct Biotechnol JXu L, Liu Y, Jang H, Nussinov R.
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Linking Superoxide Production and Scavenging in Plant Development
Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
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Mammalian evolution and human mutation burden in Rab GTPases. [PDF]
Biochem Biophys RepSidor U, Hughes GM, Simpson JC.
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The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites and acylation is critically involved in regulation of receptor constitutive activity [PDF]
, 2002 Bickmeyer, Ulf +6 more
core
Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells
Chemistry – A European Journal, Volume 32, Issue 11, 16 March 2026.We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu +5 more
wiley +1 more source
Autism spectrum disorder-associated Sema5A p.Arg676Cys drives Arf6/FE65 signaling and aberrant cell morphogenesis. [PDF]
Sci RepTakahashi M +5 more
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New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene. [PDF]
Cancer Gene TherMirzaiebadizi A, Ahmadian MR.
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Ran modulates allosteric crosstalk between importin β surfaces. [PDF]
Nat CommunKo YH +6 more
europepmc +1 more source
GTP cycling protein (GCP): An ancient player for allosteric gatekeeping. [PDF]
mLifeLiu JL.
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