Protein Hypernetworks: a Logic Framework for Interaction Dependencies and Perturbation Effects in Protein Networks [PDF]
Motivation: Protein interactions are fundamental building blocks of biochemical reaction systems underlying cellular functions. The complexity and functionality of such systems emerge not from the protein interactions themselves but from the dependencies between these interactions.
arxiv
Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats
The protein kinase Mechanistic Target of Rapamycin (mTOR) in Complex 1 (mTORC1) is regulated in part by the Ras‐related GTP‐binding proteins (Rag GTPases).
Gregory N. Kincheloe+3 more
doaj +1 more source
Identifying Interaction Sites in "Recalcitrant" Proteins: Predicted Protein and Rna Binding Sites in Rev Proteins of Hiv-1 and Eiav Agree with Experimental Data [PDF]
Protein-protein and protein nucleic acid interactions are vitally important for a wide range of biological processes, including regulation of gene expression, protein synthesis, and replication and assembly of many viruses. We have developed machine learning approaches for predicting which amino acids of a protein participate in its interactions with ...
arxiv
Roles of Heterotrimeric GTP-Binding Proteins in the Progression of Heart Failure
.: Heart failure is a major cause of death in developed countries, and the development of an epoch-making cure is desired from the viewpoint for improving the quality of life and reducing the medical cost of the patient.
Motohiro Nishida
doaj
Accurate and efficient protein embedding using multi-teacher distillation learning [PDF]
Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction prediction, and protein structure prediction.
arxiv
Interleukin-1? and GTP-binding proteins [PDF]
F. Purrello, Åke Sjöholm
openaire +3 more sources
GTP-binding Proteins in the Control of Exocytosis
P.E.R. Tatham, B.D. Gomperts
openaire +3 more sources
Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level
Homotypic membrane fusion of the endoplasmic reticulum (ER) is mediated by dynamin-like GTPase atlastin (ATL). This fundamental process relies on GTP-dependent domain rearrangements in the N-terminal region of ATL (ATLcyto), including the GTPase domain ...
Lijun Shi+12 more
doaj +1 more source
GTP-binding Proteins in Human Platelets
Yoshinori Nozawa, Koh-ichi Nagata
openaire +3 more sources