Results 161 to 170 of about 958,866 (334)

Ran-binding Protein 1 (RanBP1) Forms a Ternary Complex with Ran and Karyopherin β and Reduces Ran GTPase-activating Protein (RanGAP) Inhibition by Karyopherin β [PDF]

, 1997
Karen M. Lounsbury, Ian G. Macara
openalex   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Rho GTPase-activating protein 17 (ARHGAP17) as additional autoimmune target in ARHGAP26-IgG/anti-Ca autoantibody-associated autoimmune encephalitis. [PDF]

J Neurol, 2023
Jarius S, Haas J, Wildemann B.
europepmc   +1 more source

Identification of residues in GTPase-activating protein Src homology 2 domains that control binding to tyrosine phosphorylated growth factor receptors and p62

, 1992
Luc E. M. Marengère, Tony Pawson
openalex   +1 more source

Identification of a Sec4p GTPase-activating Protein (GAP) as a Novel Member of a Rab GAP Family [PDF]

, 1998
Li‐Lin Du, Ruth Collins, Peter Novick
openalex   +1 more source

Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas

iScience, 2019
Summary: Aberrant RAS signaling activation is common in cancers with even few Ras mutations, indicating alternative dysregulation other than genetic mutations.
Lili Li, Yichao Fan, Xin Huang, Jie Luo, Lan Zhong, Xing-sheng Shu, Li Lu, Tingxiu Xiang, Anthony T.C. Chan, Winnie Yeo, Ceshi Chen, Wai Yee Chan, Richard L. Huganir, Qian Tao   +13 more
doaj  

Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach. [PDF]

Protein Sci, 2022
Smith KP, Lee W, Tonelli M, Lee Y, Light SH, Cornilescu G, Chakravarthy S.   +6 more
europepmc   +1 more source

Ras GTPase-activating protein: a substrate and a potential binding protein of the protein-tyrosine kinase p56lck.

, 1992
Kurt E. Amrein, N Flint, B Panholzer, P Burn   +3 more
openalex   +1 more source

Conserved charged residues in the leucine-rich repeat domain of the Ran GTPase activating protein are required for Ran binding and GTPase activation [PDF]

, 1999
Jörg Haberland, Volker Gerke
openalex   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source