Results 171 to 180 of about 137,270 (354)

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Function of Rho GTPase Activating Protein 11A in Tumors

Chinese Medical Journal, 2018
Hui-Nian Zhou, Yan-Xian Ren, Long Li, Ke-Shen Wang, Zuo-Yi Jiao   +4 more
doaj   +1 more source

Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76).

, 2002
Sanjay Awasthi, Rajendra Sharma, Yusong Yang, Sharad S. Singhal, Sławomir Pikuła, Joanna Bandorowicz‐Pikuła, Shivendra V. Singh, Piotr Zimniak, Sanjay Awasthi   +8 more
openalex   +2 more sources

The yeast Rgd1p is a GTPase activating protein of the Rho3 and Rho4 proteins [PDF]

, 1999
François Doignon, Caroline Weinachter, Olivier Roumanie, Marc Crouzet   +3 more
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Activation of R-Ras GTPase by GTPase-activating Proteins for Ras, Gap1m, and p120GAP [PDF]

, 1997
Shaowei Li, Shun Nakamura, Seisuke Hattori   +2 more
openalex   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

The role of GTPase-activating protein ARHGAP26 in human cancers. [PDF]

Mol Cell Biochem, 2022
Zhang L, Zhou A, Zhu S, Min L, Liu S, Li P, Zhang S.   +6 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

GTPase-Activating Protein SH2-SH3 Domains Induce Gene Expression in a Ras-Dependent Fashion

, 1992
René H. Mede, W.L. de Laat, George A. Martin, Frank McCormick, Johannes L. Bos   +4 more
openalex   +2 more sources