Results 171 to 180 of about 958,866 (334)

Purification of GTPase-activating protein specific for the rho gene products.

open access: hybrid, 1991
Narito Morii   +4 more
openalex   +1 more source

Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src [PDF]

open access: green, 1999
Thomas K. SCHLESINGER   +3 more
openalex   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica   +4 more
wiley   +1 more source

Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms

open access: yesDiscover Oncology
This investigation explored the chemopreventive effects of eugenol on diethylnitrosamine (DENA) and acetylaminofluorene (AAF)-induced hepatocellular carcinoma (HCC) in Wistar rats.
Mohamed Y. Zaky   +7 more
doaj   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan. [PDF]

open access: yesPLoS Genet, 2022
Meraş İ   +7 more
europepmc   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

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