Differential Gene Expression in Activated Microglia Treated with Adenosine A2A Receptor Antagonists Highlights Olfactory Receptor 56 and T-Cell Activation GTPase-Activating Protein 1 as Potential Biomarkers of the Polarization of Activated Microglia. [PDF]
Lillo A +5 more
europepmc +1 more source
Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley +1 more source
Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition. [PDF]
Sun Y +7 more
europepmc +1 more source
Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
ARHGAP11A, a member of Rho GTPase activating protein family, as a prognostic biomarker linked to DNA damage response across pan-cancer. [PDF]
Tan K +7 more
europepmc +1 more source
Expression and prognostic analysis of Rho GTPase-activating protein 11A in lung adenocarcinoma. [PDF]
Chen S, Duan H, Xie Y, Li X, Zhao Y.
europepmc +1 more source
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source
Late blight pathogen targets host Rab-G3 GTPases with an atypical GTPase-activating protein. [PDF]
Liu S +13 more
europepmc +1 more source
Tumor-promoting properties of karyopherin β1 in melanoma by stabilizing Ras-GTPase-activating protein SH3 domain-binding protein 1. [PDF]
Yang F +6 more
europepmc +1 more source

