A Synaptic Ras-GTPase Activating Protein (p135 SynGAP) Inhibited by CaM Kinase II
Hong-Jung Chen+3 more
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Ca2+/Calmodulin Reverses Phosphatidylinositol 3,4,5-Trisphosphate-dependent Inhibition of Regulators of G Protein-signaling GTPase-activating Protein Activity [PDF]
Serguei G. Popov+3 more
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Rho GTPase Control of Protein Kinase C-related Protein Kinase Activation by 3-Phosphoinositide-dependent Protein Kinase [PDF]
Peter F. Flynn+3 more
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Ribonucleoprotein transport in Negative Strand RNA viruses
The genome replication of Negative‐sense, single‐stranded RNA viruses most‐often segregate in membrane‐less environments called inclusion bodies (IBs). These “organelles” usually locate far from the cell surface from where new virions are released. Here, for each viral family, we discuss how the genome progeny is transported from the IBs to reach the ...
Cédric Diot+2 more
wiley +1 more source
A New Paxillin-binding Protein, PAG3/Papα/KIAA0400, Bearing an ADP-Ribosylation Factor GTPase-activating Protein Activity, Is Involved in Paxillin Recruitment to Focal Adhesions and Cell Migration [PDF]
Akiko Kondo+5 more
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Hepatitis B virus movement through the hepatocyte: An update
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley +1 more source
RICH, a Rho GTPase-activating Protein Domain-containing Protein Involved in Signaling by Cdc42 and Rac1 [PDF]
Ninna Richnau, Pontus Aspenström
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Gαq signalling from endosomes: A new conundrum
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley +1 more source
A Mouse Homologue of the Drosophila Tumor Suppressor l(2)tid Gene Defines a Novel Ras GTPase-activating Protein (RasGAP)-binding Protein [PDF]
Grace A. Trentin+6 more
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Exosomes, autophagy, and cancer: A complex triad
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés+2 more
wiley +1 more source