Results 241 to 250 of about 958,866 (334)

A Novel GTPase-activating Protein for Rho Interacts with a PDZ Domain of the Protein-tyrosine Phosphatase PTPL1

, 1997
Jan Saras, Petra Franzèn, Pontus Aspenström, Ulf Hellman, L. Jorge Góñez, Carl‐Henrik Heldin   +5 more
openalex   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity. [PDF]

PLoS One
Rosenberg EM, Jian X, Soubias O, Jackson RA, Gladu E, Andersen E, Esser L, Sodt AJ, Xia D, Byrd RA, Randazzo PA.   +10 more
europepmc   +1 more source

Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure

European Journal of Heart Failure, EarlyView.
Heart failure (HF) with supranormal ejection fraction (HFsnEF) is an unnoticed but emerging entity in HF. This study showed that HFsnEF carries a similarly increased cardiovascular risk as HF with reduced ejection fraction (HFrEF) and distinct structural and proteomic characteristics from HFrEF, warranting a further comprehensive understanding and ...
Yasuhiko Sakata, Kotaro Nochioka, Satoshi Yasuda, Koichi Ishida, Takashi Shiroto, Jun Takahashi, Shintaro Kasahara, Ruri Abe, Shinsuke Yamanaka, Takahide Fujihashi, Hideka Hayashi, Shintaro Kato, Katsunori Horii, Kanako Teramoto, Tsutomu Tomita, Satoshi Miyata, Koichiro Sugimura, Iwao Waga, Masao Nagasaki, Hiroaki Shimokawa   +19 more
wiley   +1 more source

A Mouse Homologue of the Drosophila Tumor Suppressor l(2)tid Gene Defines a Novel Ras GTPase-activating Protein (RasGAP)-binding Protein [PDF]

, 2001
Grace A. Trentin, Xianhua Yin, Salah Tahir, Šárka Lhoták, Janet Farhang-Fallah, Yun Li, Maria Rozakis-Adcock   +6 more
openalex   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

Cdc42-Specific GTPase-Activating Protein Rga1 Squelches Crosstalk between the High-Osmolarity Glycerol (HOG) and Mating Pheromone Response MAPK Pathways. [PDF]

Biomolecules, 2021
Patterson JC, Goupil LS, Thorner J.
europepmc   +1 more source

Transient Cerebral Ischemia Increases Tyrosine Phosphorylation of the Synaptic RAS-GTPase Activating Protein, SynGAP [PDF]

, 2001
Lin Pei, R. Lucy Teves, M. Christopher Wallace, James W. Gurd   +3 more
openalex   +1 more source

Synthesis, Characterization, and Antimicrobial Activity of Copper(II) Complexes Containing Ligands Derived from Azoles and Coumarins

European Journal of Inorganic Chemistry, EarlyView.
Copper(II) complexes synthesized with coumarin‐derived ligands are tested against various strains, including C. albicans and C. tropicalis. Upon penetration into the fungal cell, these complexes induce oxidative distress and generate free radicals, leading to protein and DNA damage causing cell apoptosis.
David Ezenarro‐Salcedo, Daniela Fonseca‐López, Sandra M. Leal‐Pinto, Martha V. Roa‐Cordero, Jose D. Vargas‐Caicedo, Mario A. Macías, Bernardo A. Iglesias, Paulo C. Piquini, John J. Hurtado   +8 more
wiley   +1 more source

Rho GTPase activating protein 11A promotes tongue squamous cell carcinoma proliferation and is a transcriptional target of forkhead box M1. [PDF]

J Dent Sci
Zhang W, Bai X, Liu T, Mao Y, Zhang L, Wang W, Yu H.   +6 more
europepmc   +1 more source