Results 21 to 30 of about 137,270 (354)

FgGyp8 as a putative FgRab1 GAP is required for growth and pathogenesis by regulating FgSnc1-mediated secretory vesicles fusion in Fusarium graminearum

Journal of Integrative Agriculture, 2023
Fusarium graminearum is an important plant pathogenic fungus that causes disease and yield reduction in many cereal crops, such as wheat and barley. Gyp8 stimulates GTP hydrolysis on Ypt1 in yeast. However, the functions of Gyp8 in plant pathogenic fungi
Xing-zhi ZHANG, Shuang CHEN, Yakubu Saddeeq ABUBAKAR, Xu-zhao MAO, Peng-fei MIAO, Zong-hua WANG, Jie ZHOU, Hua-wei ZHENG   +7 more
doaj   +1 more source

Regulation of polarised growth in fungi [PDF]

, 2008
Polarised growth in fungi occurs through the delivery of secretory vesicles along tracks formed by cytoskeletal elements to specific sites on the cell surface where they dock with a multiprotein structure called the exocyst before fusing with the ...
Adamo, Adamo, Adams, Akashi, Ayad-Durieux, Bachewich, Bartnicki-Garcia, Bartnicki-Garcia, Bassilana, Bassilana, Bassilana, Behrens, Berman, Bidlingmaier, Bose, Boyce, Boyce, Boyce, Boyd, Brown, Caviston, Chant, Chapa y Lazo, Collinge, Colman-Lerner, Court, Crampin, Cvrckova, Dong, Drgonova, Dunkler, Feng, Finger, France, Gao, Girbardt, Gladfelter, Goehring, Gorovits, Gulli, Guo, Harris, Harris, Hartwell, Hergovich, Hou, Hou, Irazoqui, Jin, Karnoub, Knechtle, Kohno, Konzack, Kron, Leberer, Leberer, Leberer, Leonhard, Lew, Li, Liu, Loeb, Loeb, Longtine, Mahlert, Mata, McCollum, McCusker, Medkova, Mehta, Mendenhall, Nelson, Nonaka, Novick, Pan, Park, Pearson, Peter, Peter E. Sudbery, Philippsen, Punt, Qadota, Racki, Read, Santangelo, Schmidt, Seiler, Seiler, Sinha, Smith, Soll, Stevenson, Sudbery, Sudbery, Sudbery, Tamaskovic, Tanaka, Tcheperegine, Trinci, Verde, Versele, Virag, Virag, Walton, Walworth, Wedlich-Soldner, Wedlich-Soldner, Wendland, Wu, Yarden, Zhang, Zheng, Zheng   +112 more
core   +1 more source

Molecular architecture of Gαo and the structural basis for RGS16-mediated deactivation [PDF]

, 2008
Heterotrimeric G proteins relay extracellular cues from heptahelical transmembrane receptors to downstream effector molecules. Composed of an α subunit with intrinsic GTPase activity and a βγ heterodimer, the trimeric complex dissociates upon receptor ...
Berman, C.-K. Chen, Chan, Chen, Chen, Chen, Coleman, De Vries, Grafstein-Dunn, He, Heximer, K. C. Slep, Kimple, Koelle, Kozasa, Kozasa, Kudlacek, Lodowski, M. A. Kercher, M. I. Simon, McIntire, Neubig, Noel, P. B. Sigler, Slep, Snow, Sondek, Sunahara, T. Wieland, Tesmer, Tesmer, Valenzuela, Wang, Wilkie, Willars   +34 more
core   +4 more sources

The ADP-Ribosyltransferase Domain of the Effector Protein ExoS Inhibits Phagocytosis of Pseudomonas aeruginosa during Pneumonia

mBio, 2014
Pseudomonas aeruginosa is a Gram-negative pathogen commonly associated with nosocomial infections such as hospital-acquired pneumonia. It uses a type III secretion system to deliver effector proteins directly into the cytosol of host cells.
Stephanie M. Rangel, Latania K. Logan, Alan R. Hauser   +2 more
doaj   +1 more source

Transcriptome-based screening of intracellular pathways and angiogenesis related genes at different stages of thiram induced tibial lesions in broiler chickens

BMC Genomics, 2020
Background The Tibial dyschondroplasia (TD) in fast-growing chickens is mainly caused by improper blood circulation. The exact mechanism underlying angiogenesis and vascularization in tibial growth plate of broiler chickens remains unclear.
Ali Raza Jahejo, Ding Zhang, Sheng Niu, Raza Ali Mangi, Afrasyab Khan, Muhammad Farhan Qadir, Ajab Khan, Huan-chun Chen, Wen-xia Tian   +8 more
doaj   +1 more source

RAP1GAP (RAP1 GTPase activating protein) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on RAP1GAP (RAP1 GTPase activating protein), with data on DNA, on the protein encoded, and where the gene is implicated.
Chen, Z, Shao, X
openaire   +2 more sources

Novel role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in adhesion and migration of 32D myeloid progenitor cells [PDF]

, 2012
Rho GTPases are involved in homing and mobilization of hematopoietic stem and progenitor cells due to their impact on cytoskeleton remodeling. We have previously shown that inhibition of Rho, Rac and Cdc42 clearly impairs adhesion of normal and leukemic ...
Aschenbrenner, Frank, Bug, Gesine, Henschler, Reinhard, Hofmann, Wolf-Karsten, Kampfmann, Manuela, Komor, Martina, Ruthardt, Martin, Rüster, Brigitte Inge, Schwarz, Kerstin   +8 more
core   +1 more source

IQ-domain GTPase-activating protein 1 promotes the malignant phenotype of invasive ductal breast carcinoma via canonical Wnt pathway

Tumor Biology, 2017
IQ-domain GTPase-activating protein 1 is a scaffolding protein with multidomain which plays a role in modulating dishevelled (Dvl) nuclear translocation in canonical Wnt pathway.
Huan-Yu Zhao, Yang Han, Jian Wang, Lian-He Yang, Xiao-Ying Zheng, Jiang Du, Guang-Ping Wu, En-Hua Wang   +7 more
doaj   +1 more source

GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]

, 2015
The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna, Griffis, Anna HN, Meier, Iris, Rodrigo-Peiris, Thushani, Tilford, Bailey, Van Damme, Daniël, Zhou, Xiao   +6 more
core   +2 more sources

A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. [PDF]

, 2014
Insulin-stimulated glucose uptake in fat and muscle is mediated by the major facilitative glucose transporter Glut4. Insulin controls the trafficking of Glut4 to the plasma membrane via regulation of a series of small G proteins, including RalA and Rab10.
Chen, Xiao-Wei, Karunanithi, Sheelarani, Leto, Dara, Saltiel, Alan R, Sun, Jingxia, Uhm, Maeran, Xiong, Tingting   +6 more
core   +1 more source