Results 141 to 150 of about 1,011,564 (289)

Co-expression of Gbeta 5 Enhances the Function of Two Ggamma Subunit-like Domain-containing Regulators of G Protein Signaling Proteins [PDF]

, 2000
Regulators of G protein signaling (RGS) stimulate the GTPase activity of G protein Galpha subunits and probably play additional roles. Some RGS proteins contain a Ggamma subunit-like (GGL) domain, which mediates a specific interaction with Gbeta 5. The
Chen, Ching-Kang, He, Wei, Kovoor, Abraham, Lester, Henry A., Simon, Melvin I., Wensel, Theodore G.   +5 more
core  

WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium. [PDF]

Life Sci Alliance, 2023
Cevik S, Peng X, Beyer T, Pir MS, Yenisert F, Woerz F, Hoffmann F, Altunkaynak B, Pir B, Boldt K, Karaman A, Cakiroglu M, Oner SS, Cao Y, Ueffing M, Kaplan OI.   +15 more
europepmc   +1 more source

IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells

International Journal of Cell Biology, 2012
IQGAPs are a family of scaffolding proteins with multiple domains, named for the IQ motifs and GTPase activating protein (GAP) related domains. Despite their GAP homology, IQGAP proteins act as effectors for GTP-bound GTPases of the Ras superfamily and ...
Katie B. Shannon
doaj   +1 more source

IQ Motif Containing GTPase Activating Proteins (IQGAPs), A-Kinase Anchoring Proteins (AKAPs) and Kinase Suppressor of Ras Proteins (KSRs) in Scaffolding Oncogenic Pathways and Their Therapeutic Potential. [PDF]

ACS Omega, 2022
Mohapatra T, Dixit M.
europepmc   +1 more source

Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. [PDF]

, 1994
Paolo Fedi, Jacalyn H. Pierce, Pier Paolo Di Fiore, M H Kraus   +3 more
openalex   +1 more source

Gz, a guanine nucleotide-binding protein with unique biochemical properties [PDF]

, 1990
Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific antisera to identify the protein in tissues and to assay it ...
Casey, Patrick J., Fong, Henry K. W., Gilman, Alfred G., Simon, Melvin I.   +3 more
core  

Cdc42 GTPase-activating proteins (GAPs) regulate generational inheritance of cell polarity and cell shape in fission yeast. [PDF]

Mol Biol Cell, 2021
Pino MR, Nuñez I, Chen C, Das ME, Wiley DJ, D'Urso G, Buchwald P, Vavylonis D, Verde F.   +8 more
europepmc   +1 more source

Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor. [PDF]

Biol Open, 2021
Watanabe A, Hataida H, Inoue N, Kamon K, Baba K, Sasaki K, Kimura R, Sasaki H, Eura Y, Ni WF, Shibasaki Y, Waguri S, Kokame K, Shiba Y.   +13 more
europepmc   +1 more source

Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene. [PDF]

, 1995
To determine the functional importance of Ras in transformation by Abl oncogenes, we used a genetic approach to measure the effect of impaired Ras activity on the ability of Bcr-Abl or v-Abl to transform cells.
McLaughlin, J, Sawyers, CL, Witte, ON
core  

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P., Karl, M., Reincke, Martin, Travis, W.   +3 more
core