Results 191 to 200 of about 129,543 (335)

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

Biotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei, Sebastian Martewicz, Ramin Amiri, Meihua Cui, Nicola Elvassore, Camilla Luni   +5 more
wiley   +1 more source

P190-B Rho GTPase-Activating Protein Overexpression Disrupts Ductal Morphogenesis and Induces Hyperplastic Lesions in the Developing Mammary Gland [PDF]

, 2006
Tracy Vargo-Gogola, Brandy M. Heckman, Edward J. Gunther, Lewis A. Chodosh, Jeffrey M. Rosen   +4 more
openalex   +1 more source

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, EarlyView.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

Tyrosine phosphorylation of Ras GTPase-activating protein stabilizes its association with p62 at membranes of v-Src transformed cells.

, 1993
Soochul Park, Richard Jove
openalex   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

A Systematic Analysis of Expression and Function of RAS GTPase-Activating Proteins (RASGAPs) in Urological Cancers: A Mini-Review. [PDF]

Cancers (Basel)
Song H, Wang G, Gao G, Xia H, Jiao L, Wu K.   +5 more
europepmc   +1 more source

Supplementary Material for: Rac GTPase-Activating Protein 1 (RACGAP1) as an Oncogenic Enhancer in Esophageal Carcinoma

, 2019
Chengzeng Yin, Yuji Toiyama, Yoshinaga Okugawa, Tsunehiko Shigemori, Akira Yamamoto, Shuhei Ide, T. Kitajima, Hiroyuki Fujikawa, Hiromi Yasuda, Yoshiko Okita, J. Hiro, Shigeyuki Yoshiyama, Masaki Ohi, Toshimitsu Araki, Yao Li, M. Kusunoki   +15 more
openalex   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Roles of G proteins and their GTPase-activating proteins in platelets. [PDF]

Biosci Rep
O'Donoghue L, Smolenski A.
europepmc   +1 more source

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins. [PDF]

Sci Rep, 2019
Xie Y, Mansouri M, Rizk A, Berger P.
europepmc   +1 more source