Results 91 to 100 of about 278,687 (359)
Neurolastin, a Dynamin Family GTPase, Regulates Excitatory Synapses and Spine Density
Cell Reports, 2015 Membrane trafficking and spinogenesis contribute significantly to changes in synaptic strength during development and in various paradigms of synaptic plasticity. GTPases of the dynamin family are key players regulating membrane trafficking.
Richa Madan Lomash +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash +4 more
wiley +1 more source
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development [PDF]
, 2003 Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown.
Chan, David C. +5 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
Kinetic and Structural Analysis of the Mg2+ -binding Site of the Guanine Nucleotide-binding Protein p21 H-ras. [PDF]
, 1993 The coordination and binding of the Mg2+ ion in the nucleotide−binding site of p21 have been investigated using site−directed mutagenesis, kinetic methods, and phosphorous NMR.
Borasio, Gian Domenico +6 more
core
Atypical Rho GTPases of the RhoBTB Subfamily: Roles in vesicle trafficking and tumorigenesis [PDF]
, 2016 RhoBTB proteins constitute a subfamily of atypical Rho GTPases represented in mammals by RhoBTB1, RhoBTB2, and RhoBTB3. Their characteristic feature is a carboxyl terminal extension that harbors two BTB domains capable of assembling cullin 3-dependent ...
Ji, Wei, Rivero, Francisco
core +2 more sources
Advanced Materials, EarlyView.Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Molecular Simulations of the Ribosome and Associated Translation Factors
, 2014 The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information.
Hamed H. Alsulami (532535) +3 more
core +6 more sources
Crystallization of YIoQ, a GTPase of unknown function essential for Bacillus subtilis viability [PDF]
, 2004 YLoQ is a putative ATP/GTP-binding protein of unknown function identified from the complete sequence of the Bacillus subtilis genome. A gene-knockout programme established that yloQ is one of a set of some 270 indispensable genes for the viability of ...
Blagova, E +5 more
core +1 more source
Advanced Materials Interfaces, EarlyView.Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source