Results 151 to 160 of about 246,437 (319)
Chemistry &Biodiversity, EarlyView.Polyphenolic extracts and their fractions from five plant sources inhibit calcium oxalate and brushite crystal formation in vitro, with non‐anthocyanin fractions showing stronger anti‐lithogenic effects supported by molecular docking. ABSTRACT Nephrolithiasis, or kidney stone formation, is a widespread global health concern.
Mudassir Nazir +5 more
wiley +1 more source
ChemBioChem, EarlyView.This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann +2 more
wiley +1 more source
Structures and functions of cilia during vertebrate embryo development
Molecular Reproduction and Development, Volume 89, Issue 12, Page 579-596, December 2022., 2022 Abstract Cilia are hair‐like structures that project from the surface of cells. In vertebrates, most cells have an immotile primary cilium that mediates cell signaling, and some specialized cells assemble one or multiple cilia that are motile and beat synchronously to move fluids in one direction.
Jeffrey D. Amack
wiley +1 more source
Bistability of travelling waves and wave-pinning states in a mass-conserved reaction-diffusion system: From bifurcations to implications for actin waves [PDF]
arXivEukaryotic cells demonstrate a wide variety of dynamic patterns of filamentous actin (F-actin) and its regulators. Some of these patterns play important roles in cell functions, such as distinct motility modes, which motivate this study. We devise a mass-conserved reaction-diffusion model for active and inactive Rho-GTPase and F-actin in the cell ...
arxiv
Stimulation by prostaglandin E2 of a high-affinity GTPase in the secretory granules of normal rat and human pancreatic islets [PDF]
, 1994 Anjaneyulu Kowluru, Stewart A. Metz
openalex +1 more source
ChemBioChem, EarlyView.Regulated intramembrane proteolysis is crucial for functional proteome in all kingdoms of life. The task of cleaving transmembrane proteins within the unique environment of the lipid bilayer presents biochemical challenges that has been solved by integral membrane proteases (IMPRs).
Hannah Fremlén, Björn M. Burmann
wiley +1 more source
Effect of antimitotic drugs on tubulin GTPase activity and self-assembly.
, 1979 T David-Pfeuty +2 more
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Protein-Tyrosine Kinases Regulate the Phosphorylation, Protein Interactions, Subcellular Distribution, and Activity of p21rasGTPase-Activating Protein [PDF]
, 1991 Michael F. Moran +4 more
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First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery
ChemBioChem, EarlyView.Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger +7 more
wiley +1 more source