Results 181 to 190 of about 274,715 (359)

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

The role of small GTPase Rac1 in stress signaling [PDF]

, 2014
Burçin Güngör
openalex   +1 more source

Regulation of Ras p21 and RalA GTPases activity in mammary epithelial cells by quinine

, 2021
Laya Esmati
openalex   +1 more source

Functional Analysis of the Contribution of RhoA and RhoC GTPases to Invasive Breast Carcinoma [PDF]

, 2004
Kaylene J. Simpson, Aisling S. Dugan, Arthur M. Mercurio   +2 more
openalex   +1 more source

Detection of Small GTP Binding Proteins Showing GTPase and GTP/ATP Binding Activities in the Ovary of the American Cockroach, Periplaneta Americana, during Oogenesis [PDF]

, 2014
Mohamed Elmogy
openalex   +1 more source

Conformational control of small GTPases by AMPylation [PDF]

, 2020
Katja Barthelmes, Evelyn Ramcke, Hyun-Seo Kang, Michael Sattler, Aymelt Itzen   +4 more
openalex   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, EarlyView.
Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and posttranscriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron splicing ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Mechanisms of interferon-beta-induced inhibition ofToxoplasma gondiigrowth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1 [PDF]

, 2015
Motamed Elsayed Mahmoud, Fumiki Ui, Doaa Salman, Maki Nishimura, Yoshifumi Nishikawa   +4 more
openalex   +1 more source

CD14 plays a critical role in pain and inflammation across multiple models of post‐traumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine OA models that vary in severity of pathology and rate of progression, to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Global molecular landscape of early MASLD progression in human obesity. [PDF]

Elife
Zhao Q, De Nardo W, Wang R, Zhong Y, Keles U, Sakalauskaite G, Zhao LN, Tay H, Youhanna S, Yan M, Xie Y, Kim Y, Lee S, Lim RL, Teo G, Narayanaswamy P, Burton PR, Lauschke VM, Choi H, Watt MJ, Kaldis P.   +20 more
europepmc   +1 more source