Results 61 to 70 of about 6,079 (194)

Characterization of nerve-induced relaxation of gastrointestinal sphincteric smooth muscle in a South American opossum (Didelphis albiventris)

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The presence of inhibitory nonadrenergic noncholinergic (NANC) intrinsic innervation of the circular muscle of the gastrointestinal sphincters of the South American (SA) opossum was investigated in vitro.
N.M. Matsuda, R.B. Oliveira, G. Ballejo
doaj   +1 more source

Decreases in mucosally‐evoked tachykinin signaling pathways can explain age‐related reductions in murine colonic motility patterns

open access: yesNeurogastroenterology &Motility, Volume 36, Issue 11, November 2024.
The natural aging process can reduce lower bowel motility, leading to an increased incidence of chronic constipation. Aging reduces tachykinin signaling in the distal colon reducing colonic motility. Medicines that increase tachykinin signaling could be useful for treating chronic constipation in older people.
Mark S. Yeoman   +6 more
wiley   +1 more source

Modulation of Noradrenergic Neurotransmission in Isolated Rat Radial Artery

open access: yesJournal of Pharmacological Sciences, 2009
The present study was designed to characterize the neurogenic contraction of rat radial artery. Electrical field stimulation (EFS) evoked frequency-dependent contraction that was abolished by tetrodotoxin (neuronal Na+ channel blocker), guanethidine ...
Ana Cristina Martínez   +6 more
doaj   +1 more source

Cardiac Arrhythmias in Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension: Mechanistic Insights, Pathophysiology, and Outcomes

open access: yesAnnals of Noninvasive Electrocardiology, Volume 29, Issue 5, September 2024.
This review provides an overview of the latest evidence on this subject, spanning from the molecular mechanisms underlying arrhythmias in the hypertrophied or failing right heart to the clinical aspects of epidemiology, diagnosis, and treatment.
Abdulrahman Abouzaid   +7 more
wiley   +1 more source

The Lower Urinary Tract Science Group—ICI‐RS. 7th June 2023 record of a meeting at Bristol University, UK

open access: yesNeurourology and Urodynamics, Volume 43, Issue 6, Page 1253-1260, August 2024.
Abstract Aims The aim of a preliminary session of the International Continence on Incontinence—Research Society (ICI‐RS) was to provide a forum for an international group of experimental scientists, who are members of ICI‐RS, to explain their on‐going work to fellow laboratory scientists, to obtain feedback about future directions and discuss potential
Christopher Fry
wiley   +1 more source

Local haemorrhage induced by Bothrops jararaca venom: relationship to neurogenic inflammation

open access: yesMediators of Inflammation, 2000
We investigated morphological alterations induced by s.c. injection of 2.5 μg of Bothrops jararaca venom in rats. Intense disorganisation of collagen fibres was observed 1 min after the venom injection, particularly at regions near vessels and nerves ...
Luis Roberto C. Gonçalves   +1 more
doaj   +1 more source

Essential Role of the Interstitial Cells of Cajal in Nitric Oxide-Mediated Relaxation of Longitudinal Muscle of the Mouse Ileum

open access: yesJournal of Pharmacological Sciences, 2004
The role of interstitial cells of Cajal (ICC) in electrical field stimulation (EFS)-induced neurogenic responses in ileum was studied by using the ICC-deficient mutant (SLC-W/WV) mouse and its wild type.
Tadayoshi Takeuchi   +5 more
doaj   +1 more source

A novel reuptake inhibitor, IP2015, induces erection by increasing central dopamine and peripheral nitric oxide release

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 15, Page 2566-2582, August 2024.
Background and Purpose An estimated 40% of patients with erectile dysfunction have a poor prognosis for improvement with currently available treatments. The present study investigated whether a newly developed monoamine transport inhibitor, IP2015, improves erectile function.
Simon Comerma‐Steffensen   +8 more
wiley   +1 more source

Evidence for the involvement of peripheral -adrenoceptors in delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats

open access: yesBrazilian Journal of Medical and Biological Research, 2013
Dipyrone (Dp), 4-aminoantipyrine (AA), and antipyrine (At) delay liquid gastric emptying (GE) in rats. We evaluated adrenergic participation in this phenomenon in a study in male Wistar rats (250-300 g) pretreated subcutaneously with guanethidine (GUA ...
A.M. Vinagre, E.F. Collares
doaj   +1 more source

Nuclear medicine in endocrine tumours [PDF]

open access: yes, 2011
C
Peremans, Kathelijne   +1 more
core   +2 more sources

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