Results 81 to 90 of about 6,045 (297)
Comparison of Dried Blood Spot Sampling Methods for RNA‐Based Biomarker Measurement in Anti‐Doping
Drug Testing and Analysis, EarlyView.This study demonstrates that RNA‐based biomarkers of erythropoiesis, ALAS2 and CA1, can be reliably quantified across commonly used DBS sampling matrices, including venous and capillary blood spotted on cellulose cards and the Tasso‐M20 device. ABSTRACT Dried blood spot (DBS) sampling offers logistical advantages, but it remains unexplored whether ...
Jacob Bejder +9 more
wiley +1 more source
, 2016 Simple preparation methods of modified guanidines have been explored as potential chiral superbases. Thus, 3,7,8-trisubstituted and 3,6,7,8-tetrasubstituted 1,4,6-triazabicyclooctene systems were prepared from (1S,2S)-1,2-diphenylethylenediamine through ...
Keiko Fukuda (2640976) +5 more
core +2 more sources
Titanacarborane Amide Catalyzed Transamination of Guanidines
, 2016 This work describes a catalytic transamination of guanidines with a broad substrate scope of primary, secondary, heterocyclic, aliphatic, and aromatic amines, using 5−10 mol % of the half-sandwich titanacarborane amide [σ:η1:η5-(OCH2)(Me2NCH2)C2B9H9]Ti ...
Hao Shen (195461), Zuowei Xie (1425799)
core +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Synthetic routes towards guanidines of biological interest
, 2014 THESIS 10430The Rozas laboratory has been interested in the synthesis and biological evaluation of guanidine containing molecules for the past ten years.
Shaw, Julian W.
core
Synthesis of Orthogonally N-Protected, C-4 Functionalized Cyclic Guanidines from L-Serine
, 2017 International audienceA straightforward and efficient preparation of 5-membered cyclic guanidines bearing an ester, a hydroxymethyl or a Weinreb amide functional group at C-4 is described from L-serine.
Suárez Ordóñez, Rosa +5 more
core +1 more source
Ion‐Enriched Porous Organic Polymer for Gold Recovery From E‐Waste
EcoEnergy, EarlyView.A novel ion‐enriched porous organic polymer was designed and synthesized. It exhibits ultrahigh gold adsorption efficiency with capacity up to 1530.9 mg g−1, and also shows selective capture ability towards gold ions in the actual CPU leaching solution, demonstrating its promising potential for gold recovery from actual e‐waste.
Rui Zhang +8 more
wiley +1 more source
Copper-catalyzed oxidative three-component synthesis of N, N',N″-trisubstituted guanidines.
, 2013 International audienceA copper-catalyzed three-component synthesis of trisubstituted N-aryl guanidines involving cyanamides, arylboronic acids, and amines has been developed. This operationally simple oxidative process, which is performed in the presence
Li, Jihui, Neuville, Luc
core +1 more source
Optimized iCIEF Fractionation Enables Deep Profiling of Antibody Drug Conjugate Charge Heterogeneity
ELECTROPHORESIS, EarlyView.This study developed and optimized an iCIEF fractionation method to characterize ADC charge variants. The optimized approach enabled stable separation, identification of major PTMs, and drug‐load distributions across light and heavy chains. ABSTRACT Antibody drug conjugates (ADCs) are a novel class of therapeutic drugs that combine selectivity of an ...
Eunju Jang +2 more
wiley +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Equine Veterinary Journal, EarlyView.Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source