Results 101 to 110 of about 158,534 (314)
Non‐traditional encryption methods: Moving toward electrochemical cryptography
Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022 Abstract Cybersecurity and encryption are critical in diverse applications from simple emails to high‐priority government secrets. It is best accomplished by an “unbreakable” cipher or one which is only decrypted by those with a matching cipher key to the initial encryption.
Giana Biddle +2 more
wiley +1 more source
Molecular Dynamics Studies of Changes in the DNA- Structure as Result of Interactions with Cisplatin [PDF]
arXiv, 2011 The 3'-monofunctional adduct of cisplatin and d(CTCTG*G*TCTC)2 duplex DNA in solvent with explicit counter ions and water molecules were subjected to MD- simulation with AMBER force field on a nanosecond time scale. In order to simulate the closure of the bond between the Pt and 5'-guanine-N7 atoms, the forces acting between them were gradually ...
arxiv
Thermoelectric effect in molecular electronics [PDF]
, 2003 We provide a theoretical estimate of the thermoelectric current and voltage over a Phenyldithiol molecule. We also show that the thermoelectric voltage is (1) easy to analyze, (2) insensitive to the detailed coupling to the contacts, (3) large enough to be measured and (4) give valuable information, which is not readily accessible through other ...
arxiv +1 more source
Sugar‐sensing swodkoreceptors and swodkocrine signaling
Animal Models and Experimental Medicine, EarlyView.Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley +1 more source
Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship
Annals of Neurology, EarlyView.Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino +4 more
wiley +1 more source
Crystal structure of disodium 2-amino-6-oxo-6,7-dihydro-1H-purine-1,7-diide heptahydrate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, disodium 2-amino-6-oxo-6,7-dihydro-1H-purine-1,7-diide heptahydrate, 2Na+·C5H3N5O2−·7H2O, the structure is composed of alternating (100) layers of guanine molecules and hydrated Na+ ions. Within the guanine layer, the molecules are
Dvir Gur, Linda J. W. Shimon
doaj +1 more source
Molecules, 2018 The formation of a guanine quadruplex DNA structure (G4) is known to repress the expression of certain cancer-related genes. Consequently, a mutated G4 sequence can affect quadruplex formation and induce cancer progression. In this study, we developed an
Shuntaro Takahashi +5 more
doaj +1 more source
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Hidden triangular grating structures in biogenic guanine platelet
AIP Advances, 2020 A platelet made of guanine is used to control light reflection from the bodies of fish, and an assembly of the platelets acts as an efficient photonic crystal. This work reveals that internal structures exist in addition to the smooth platelet surface. A
Masakazu Iwasaka
doaj +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source