Results 111 to 120 of about 316,659 (284)
Generation, repair and replication of guanine oxidation products
Genes and Environment, 2017 Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication.
Katsuhito Kino +4 more
doaj +1 more source
Advanced Science, EarlyView.A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen +8 more
wiley +1 more source
Reply to “Comment on ‘Proton Transfer of Guanine Radical Cations Studied by Time-Resolved Resonance Raman Spectroscopy Combined with Pulse Radiolysis’” [PDF]
, 2016 Jungkweon Choi +5 more
openalex +1 more source
RNA G‐Quadruplex RIBOTAC‐Mediated Targeted Degradation of lncRNA TERRA
Advanced Science, EarlyView.This study introduces a selective RNA degradation strategy targeting long noncoding RNA (lncRNA) TERRA, upregulated in ALT (alternative lengthening of telomeres) cancer cells. Using ribonuclease‐targeting chimeras (RIBOTACs), RNase L is recruited to catalytically degrade TERRA, uncovering a novel approach to affect a disease associated lncRNA in ALT ...
Elias Khaskia +2 more
wiley +1 more source
Clinics, 2019 OBJECTIVE: In this study, the relationship between osteoporotic vertebral fractures and 9041 Guanine/Adenine and 3673 Guanine/Adenine polymorphisms related to the vitamin K epoxide reductase complex subunit-1 (VKORC1) gene in postmenopausal women with ...
Merih Ozgen +9 more
doaj +1 more source
Barley guanine nucleotide exchange factor Hv GEF14 is an activator of the susceptibility factor Hv RACB and supports host cell entry by Blumeria graminis f.sp. hordei [PDF]
, 2021 Adriana Trutzenberg +2 more
openalex +1 more source
Advanced Science, EarlyView.This work introduces a label‐free SERS‐AI platform for rapid and interpretable diagnosis of polymicrobial urinary tract infections. By integrating Au@Ag@bPEI substrates with a CNN‐CBAM model, the system enables accurate bacterial identification and proportion prediction, while highlighting biologically relevant Raman features.
Zhonghua Shen +10 more
wiley +1 more source
Advanced Science, EarlyView.A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang +7 more
wiley +1 more source
Advanced Science, EarlyView.Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai +7 more
wiley +1 more source
Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin [PDF]
, 2013 Inmaculada López-Sánchez +5 more
openalex +1 more source