Results 111 to 120 of about 158,534 (314)
Generation, repair and replication of guanine oxidation products
Genes and Environment, 2017 Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication.
Katsuhito Kino +4 more
doaj +1 more source
Magnetic motion of biogenic guanine crystal plate combined with Fe2O3 nanoparticles
AIP Advances, 2020 To reduce the magnetic field amplitude required to orient guanine crystal plates, we have attached magnetic nanoparticles to these guanine crystal plates.
Ryosuke Nagai +5 more
doaj +1 more source
GC3 Biology in Eukaryotes and Prokaryotes [PDF]
DNA Methylation - From Genomics to Technology, 2012, pp 55-68, 2012 We describe the distribution of Guanine and Cytosine (GC) content in the third codon position (GC3) distributions in different species, analyze evolutionary trends and discuss differences between genes and organisms with distinct GC3 levels. We scrutinize previously published theoretical frameworks and construct a unified view of GC3 biology in ...
arxiv
Optical Probes for Cellular Imaging of G‐quadruplexes: Beyond Fluorescence Intensity Probes
Angewandte Chemie International Edition, Accepted Article.The study of G‐quadruplex (G4) structures that form in DNA and RNA is a rapidly growing field, which has evolved from in vitro studies of isolated G4 sequences to genome‐wide detection of G4s in a cellular context. This work has revealed the tangible and significant effects that G4s may have on biological regulation.
Jenna Robinson +3 more
wiley +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Guanine Metabolism in Fishes. I. The Occurrence of a Guanine-Deaminating Enzyme in Fish Skin. [PDF]
, 1957 Per Eric Lindahl +6 more
openalex +1 more source
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Clinics, 2019 OBJECTIVE: In this study, the relationship between osteoporotic vertebral fractures and 9041 Guanine/Adenine and 3673 Guanine/Adenine polymorphisms related to the vitamin K epoxide reductase complex subunit-1 (VKORC1) gene in postmenopausal women with ...
Merih Ozgen +9 more
doaj +1 more source
The occurrence of methylated guanines in ribonucleic acids from several sources [PDF]
, 1959 Johan Smith, David B. Dunn
openalex +1 more source
Ribozyme‐catalyzed site‐specific labeling of RNA using O6‐alkylguanine SNAP‐tag substrates
Angewandte Chemie International Edition, Accepted Article.Site‐specific modification of RNAs with functional handles enables studies of RNA structure, fate, function, and interactions. Ribozymes provide an elegant way to covalently modify an RNA of interest (ROI). Here, we report that the methyltransferase ribozyme MTR1 can be employed as a versatile tool for RNA modification and labeling.
Manisha B. Walunj +3 more
wiley +1 more source