Results 131 to 140 of about 38,557 (248)

Theoretical Study of Hydrated Copper(II) Interactions with Guanine:  A Computational Density Functional Theory Study

, 2008
Optimization of the hydrated Cu(II)(N7−guanine) structures revealed a number of minima on the potential energy surface. For selected structures, energy decompositions together with the determination of electronic properties (partial charges and electron ...
Manoj K. Shukla (736256), Matěj Pavelka (2643880), Jaroslav V. Burda (1957360), Jerzy Leszczynski (1371450)   +3 more
core   +1 more source

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang, Fengfeng Xiao, Ruie Chen, Cuixia Lu, Yi Ju, Mingqing Yuan, Yunlu Dai, Liewei Wen   +7 more
wiley   +1 more source

The Mechanism of the Selective Antiproliferation Effect of Guanine-Based Biomolecules and Its Compensation

, 2019
As endogenous biomolecules, guanine, guanine-based nucleosides, and nucleotides are essential for cellular DNA/RNA synthesis, energy metabolism, and signal transduction.
Linlin Wang (289071), Nan Zhang (46264), Xiangjun Liu (1778443), Junyan Wang (4738518), Tao Bing (407658), Junqing He (6733532), Dihua Shangguan (359783), Luyao Shen (4738515)   +7 more
core   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Guanine crystal formation by the unicellular organism Phacotus lenticularis is part of a cellular stress response.

PLoS ONE
Organic crystals, and in particular guanine crystals, are widely used by multicellular organisms for manipulating light and producing structural colors.
Noy Shaked, Andrea Sorrentino, Neta Varsano, Sefi Addadi, Ziv Porat, Iddo Pinkas, Steve Weiner, Lia Addadi   +7 more
doaj   +1 more source

Guanine [PDF]

, 2020
openaire   +1 more source

Recent Progress of Biomass‐Derived Nitrogen‐Doped Carbon Materials as Electrocatalysts: Carbonization, Functionalization, and Applications

Carbon Energy, EarlyView.
Integrating renewable energy with electrochemical conversion and storage is crucial for sustainable energy solutions. Nitrogen‐doped biomass‐derived carbon materials have emerged as effective catalysts for key reactions such as ORR, HER, and CO2RR. This review explores their synthesis, functionalization, characterization, and catalytic applications ...
Shilong Fu, Haiping Yang, Wiebren de Jong, Ruud Kortlever   +3 more
wiley   +1 more source

Underlying charge-transfer mechanism of visible light emission in guanine crystals

Communications Chemistry
Biogenic guanine crystals found in various aquatic and terrestrial animals, show unique optical properties that include structural coloration as well as reflectance and have intrigued researchers for over a century.
Aditya Prasun, Ravindra Vishwakarma, Kangkan Sharmah, Ankur Kanti Guha, Ranjit Thakuria, Tridib K. Sarma   +5 more
doaj   +1 more source

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

Carbon Energy, EarlyView.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie, Jia Ouyang, Manu Suvarna, Xiangzhou Yuan, Matthew R. Hill, Uwe Bornscheuer, Huiyan Zhang, Yong Sik Ok   +7 more
wiley   +1 more source

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

Chemistry – A European Journal, EarlyView.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup, Peter Reinholdt, Kasper Munch Beck, Michael Petersen, Jean‐Louis Mergny, Poul Nielsen   +5 more
wiley   +1 more source