Results 131 to 140 of about 283,665 (235)

Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers

Ibrain, EarlyView.
This review highlights the potential of gold nanoparticles (AuNPs) in overcoming the blood‐brain barrier (BBB) to improve brain tumor treatment. By enabling targeted drug delivery and enhancing therapies like radiotherapy, phototherapy, and chemotherapy, AuNPs offer a promising approach for safer, more effective treatments of glioblastoma and other ...
Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi   +4 more
wiley   +1 more source

Scalable control of stem cell fate by riboswitch-regulated RNA viral vector without genomic integration. [PDF]

Mol Ther
Kim N, Yokobayashi Y.
europepmc   +1 more source

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang, Steven C. Moore, Sheng Fu, Xiaoyu Wang, Demetrius Albanes, Stephanie J. Weinstein, Kai Yu, Rachael Z. Stolzenberg‐Solomon   +7 more
wiley   +1 more source

The diagnosis and treatment of disorders of nucleic acid/nucleotide metabolism associated with epilepsy. [PDF]

Acta Epileptol
Shi Y, Wei Z, Feng Y, Gan Y, Li G, Deng Y.   +5 more
europepmc   +1 more source

Rapid and Visual Detection of Mycobacterium tuberculosis Complex Based on Multiplex Recombinase Polymerase Amplification

iLABMED, EarlyView.
We developed an on‐site detection platform for rapid detection of Mycobacterium tuberculosis complex (MTBC) based on the IS1081 gene. The platform utilizes real‐time multiplex recombinase polymerase amplification (mRPA) to achieve a reaction time of less than 30 min.
Xiaoyan Tan, Yongcong Li, Xufu Xiang, Wei Wu, Gang Wang, Sai Zhang   +5 more
wiley   +1 more source

Revealing the Crystal Structure of the Purine Base Xanthine with Three-Dimensional (3D) Electron Diffraction. [PDF]

Cryst Growth Des
Leung HW, Copley RCB, Lampronti GI, Day SJ, Saunders LK, Johnstone DN, Midgley PA.   +6 more
europepmc   +1 more source

Rapid Diagnostic Testing for Infective Endocarditis and Myocarditis Using Nanopore Targeted Sequencing

iLABMED, EarlyView.
This research presents a method based on nanopore targeted sequencing (NTS) with pathogen‐specific panels for testing infective endocarditis (IE) and myocarditis. The NTS achieved a detection limit of 20 copies/test for the IE target panel and 10 copies/test for the myocarditis target panel.
Aisi Fu, Xian Wang, Zhiyong Shen, Jiashuang Gu, Ting Zhang, Feiyan Wang, Shiyu Jia, Linmei Yang, Feng Li, Jie Geng, Jun Cheng   +10 more
wiley   +1 more source

Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition. [PDF]

Nat Commun
Shi X, Li M, Liu Z, Tiessen J, Li Y, Zhou J, Zhu Y, Mahesula S, Ding Q, Tan L, Feng M, Kageyama Y, Hara Y, Tao JJ, Luo X, Patras KA, Lorenzi PL, Huang S, Stevens AM, Takahashi K, Issa GC, Samee MAH, Agathocleous M, Nakada D.   +23 more
europepmc   +1 more source

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens, Anita Thyagarajan, Jeffrey B. Travers, Ravi P. Sahu   +3 more
wiley   +1 more source

Genome Analysis and In Vitro Assay of Probiotic Properties of <i>Bacillus paranthracis</i> YC03 with Urate-Lowering Potential. [PDF]

Microorganisms
Cao X, Zhang Y, Xu Q, Yan H.
europepmc   +1 more source