Results 131 to 140 of about 158,534 (314)

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

open access: yesAnimal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah   +4 more
wiley   +1 more source

The next 10 years of behavioural genomic research

open access: yesJCPP Advances, Volume 2, Issue 4, December 2022., 2022
Three transformative developments for behavioural genomic research in the next 10 years are described. First, behavioural genomic research will use dimensional measures to reveal the hierarchical genetic architecture of psychopathology. A second direction for behavioural genomic research will be to investigate causa models of GE interplay.
Robert Plomin
wiley   +1 more source

Severe myelosuppression and alopecia after thiopurine initiation in a patient with NUDT15 deficiency

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Thiopurines are a class of immunosuppressant and antineoplastic agents. They are widely used in the treatment of inflammatory bowel disease, haematological malignancies and autoimmune diseases, but can cause significant toxicity. Inherited gene mutations are now recognized as independent risk factors for severe adverse drug reactions to thiopurines ...
Annie Siyu Wu   +3 more
wiley   +1 more source

Telomere‐to‐telomere reference genome reveals subgenome divergence and large structural variants in Capsella bursa‐pastoris (Brassicaceae)

open access: yesBiological Diversity, EarlyView.
This study presents a subgenome‐resolved telomere‐to‐telomere reference genome of Capsella bursa‐pastoris, named Cbp_T2T, constructed using PacBio HiFi reads, Nanopore ultra‐long reads, and Hi‐C data. Notable divergences were observed between its subgenomes, and comparative genomics identified two large inversions within the species.
Xin Liu   +4 more
wiley   +1 more source

Electron channels in biomolecular nanowires [PDF]

open access: yesJournal of Physical Chemistry B 108, 2509 (2004), 2004
We report a first-principle study of the electronic and conduction properties of a quadruple-helix guanine wire (G4-wire), a DNA-derivative, with inner potassium ions. The analysis of the electronic structure highlights the presence of energy manifolds that are equivalent to the bands of (semi)conducting materials, and reveals the formation of extended
arxiv  

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

open access: yesChemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang   +8 more
wiley   +1 more source

Cucurbit[7]uril‐Styryl Dye Complexes for Fluorescent Recognition of DNA and Cell Imaging

open access: yesChemBioChem, EarlyView.
Recognition properties in solution and in cancer cells: a two dicationic cyanine dyes with different functionalities were developed and studied for their fluorescent properties, cytotoxicity and cellular imaging. The effect of encapsulation was checked using synthetic molecular container of cucurbit[7]uril.
Ekaterina Y. Chernikova   +7 more
wiley   +1 more source

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