Results 141 to 150 of about 158,534 (314)

Guanine: Formation during the Thermal Polymerization of Amino Acids [PDF]

, 1964
Cyril Ponnamperuma, Richard S. Young, Elaine F. Munoz, B. Kaiser McCaw   +3 more
openalex   +1 more source

Wireframe DNA Origami Capable of Vertex‐protruding Transformation

ChemBioChem, EarlyView.
A wireframe DNA origami capable of vertex‐protruding transformation is reported. Spacer strands between vertices and edges introduce vertex‐specific flexibility, enabling designed vertex protrusion. Through DNA hybridization and strand displacement reactions, the structure is reversibly transformed between open‐ and closed‐forms. This vertex‐protruding
Yosuke Ochi, Wataru Kato, Yoichi Tsutsui, Yuki Gomibuchi, Daichi Tominaga, Keisuke Sakai, Takeshi Araki, Suzunosuke Yoshitake, Takuo Yasunaga, Yusuke V. Morimoto, Kazuhiro Maeda, Junichi Taira, Yusuke Sato   +12 more
wiley   +1 more source

THE UPTAKE OF GUANINE, URACIL, LYSINE AND GLYCINE BY ASCITES CELLS PRETREATED WITH AZASERINE AND 6-THIOGUANINE [PDF]

, 1963
David H. Adams
openalex   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

ChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout, Marie‐Christine Maurel   +1 more
wiley   +1 more source

Are β3‐adrenoceptor gene polymorphisms relevant for urology?

Neurourology and Urodynamics, Volume 42, Issue 1, Page 33-39, January 2023., 2023
Abstract Aims β3‐adrenoceptors (ARs) are an important drug target for the treatment of overactive bladder syndrome (OAB) and are under investigation for other indications. The human β3‐AR gene is polymorphic; an exchange of amino acid tryptophan (Trp) for arginine (Arg) in position 64 of the receptor protein is the most frequent and best‐studied ...
Martin C. Michel
wiley   +1 more source

Studies on guanine deaminase and its inhibitors in rat tissue [PDF]

, 1967
Sudhir Kumar, Veena Josan, Kuldeep Sanger, Κ. Κ. Tewari, P. S. Krishnan   +4 more
openalex   +1 more source

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

Cell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee, Matthew Phanchana, Phorutai Pearngam, Nopphon Petchyam, Kornkanok Promthep, Ponlawit Wisomka, Suchanoot Kutpruek, Supitcha Pannengpetch, Tanya Prasertporn, Sujira Mukda, Piyarat Govitrapong, Chutikorn Nopparat   +11 more
wiley   +1 more source

The Fluorescence of Guanine and Guanosine. Effects of Temperature and Viscosity on Fluorescence Polarization and Quenching. [PDF]

, 1967
Hans Chr. Børresen, Karl–Erik L. Eriksson, Olof Vesterberg, Åke Åkeson, Hugo Theorell, R. Blinc, S. Paušak, L. Ehrenberg, J. Dumanović   +8 more
openalex   +1 more source

A Cytotoxic Indazole‐based Gold(III) Carboxamide Pincer Complex Targeting DNA Through Dual Binding Modes of Groove Binding and Alkylation

Chemistry – A European Journal, EarlyView.
Toward new gold(III) anticancer agents. Herein, we report on an indazole‐based gold(III) carboxamide pincer complex exhibiting significant cytotoxicity, likely mediated through dual interactions with DNA. Mechanistic investigations suggest that the complex binds to the DNA and forms specific interactions with nucleotide bases.
Rufaro Razuwika, Sheldon Sookai, Ruth Aronson, Mandeep Kaur, Orde Q. Munro   +4 more
wiley   +1 more source

Sensing guanine and its derivatives: From molecular recognition to applications

Sensors and Actuators Reports, 2020
Guanine plays an indispensable role in building nucleic acids, and its derivatives take part in various cellular functions such as regulating biological reactions and signal transduction.
Yuqing Li, Juewen Liu
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