Results 161 to 170 of about 283,665 (235)

Effect of Explicit Hydration on the Cisplatin Reaction Mechanism with Adenine and Guanine. [PDF]

open access: yesMolecules
Salazar-Barrientos JI   +6 more
europepmc   +1 more source

Clustering of Membrane Receptors: Insights from DNA Origami‐Based Approaches

open access: yesSmall, EarlyView.
Receptor clustering critically influences cell signaling, yet its precise regulation remains elusive. This review highlights how DNA origami structures serve as nanoscale tools to uncover receptor organization and provide new insights into signal transduction.
Carmen M. Domínguez   +1 more
wiley   +1 more source

Rare GNAO1 Variant Presenting with Deep Brain Stimulation‐Responsive Jaw‐Opening Dystonia

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Fabian Maass   +4 more
wiley   +1 more source

Exploring 2D Graphene‐Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective

open access: yesSmall Science, EarlyView.
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos   +2 more
wiley   +1 more source

Targeted siRNA Delivery Using Cetuximab‐Conjugated Starch for Epidermal Growth Factor Receptor‐Driven Head and Neck Squamous Cell Carcinoma

open access: yesSmall Science, EarlyView.
A starch‐based carrier conjugated to cetuximab enables targeted siRNA delivery to epidermal growth factor receptor‐overexpressing tumors. The complexes exhibit dual passive and active tumor targeting, effective cellular uptake, and gene silencing, offering a versatile platform for RNA therapeutics in head and neck cancer.
Chen Benafsha   +10 more
wiley   +1 more source

Dissociation Constant (Kd) Measurement for Small‐Molecule Binding Aptamers: Homogeneous Assay Methods and Critical Evaluations

open access: yesSmall Methods, EarlyView.
The characteristics of aptamer is most commonly represented by the dissociation constant (Kd), which is critical for aptamer optimization. Here, the assays used to evaluate Kd, including labeled and label‐free assays, are evaluated and suggestions are made to ensure that true values are obtained, while other methods are cautioned.
Stefen Stangherlin   +2 more
wiley   +1 more source

Author Correction: Antisense mediated blockade of Dickkopf 1 attenuates tumor survival, metastases and bone damage in experimental osteosarcoma. [PDF]

open access: yesSci Rep
Haskell A   +10 more
europepmc   +1 more source

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