Results 151 to 160 of about 84,425 (312)

Multiple Guanine Nucleotide Exchange Factors Mediate Glucose-Induced Rac1 Activation and Insulin Secretion: Is It Precise Regulatory Control or a Case of Two Peas from the Same Pod? [PDF]

ACS Pharmacol Transl Sci, 2021
Kowluru A.
europepmc   +1 more source

Pleckstrin Homology Domain-mediated Activation of the Rho-specific Guanine Nucleotide Exchange Factor Dbs by Rac1 [PDF]

, 2004
Li Cheng, Gwendolyn M. Mahon, Elena V. Kostenko, Ian P. Whitehead   +3 more
openalex   +1 more source

A GmeIF2B5‐GmPRX4 Regulatory Axis Divergently Governs Drought‐Lignin and Salt‐Ion Homeostasis in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Abiotic stresses severely constrain soybean productivity worldwide. Here we demonstrate that gmeif2b5 (eukaryotic initiation factors) mutants confer dual stress tolerance through coordinated mechanisms. Integrative RNA‐Seq and protein interaction analyses revealed that gmeif2b5 mutants increase lignin deposition to increase drought resilience ...
Juan Liu, Yanzhong Huang, Xiaowan Fang, Han Gou, Huidong Xuan, Sushuang Deng, Lu Li, Yanjia Wang, Xiushuai Wang, Ling Gan, Nannan Zhang, Haoran Luo, Yaolan Bai, Qin Liu, Han Xing, Jinming Zhao, Na Guo   +16 more
wiley   +1 more source

Conformations and binding pockets of HRas and its guanine nucleotide exchange factors complexes in the guanosine triphosphate exchange process. [PDF]

J Comput Chem, 2022
Xiong Y, Zeng J, Xia F, Cui Q, Deng X, Xu X.   +5 more
europepmc   +1 more source

Characterization of ROP GTPase-activated Arabidopsis receptor-like cytoplasmic kinases (RLCK class VI_A) [PDF]

, 2011
Plants have to respond and adapt to a variety of continuously changing environmental factors in order to establish an appropriate developmental strategy to ensure survival. There are ample data showing that protein phosphorylation/dephosphorylation plays
Jurca Elena Manuela
core  

Multidomain organization of eukaryotic guanine nucleotide exchange translation initiation factor eIF‐2B subunits revealed by analysis of conserved sequence motifs [PDF]

, 1995
Eugene V. Koonin
openalex   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling. [PDF]

Small GTPases, 2021
Tong SJ, Wall AA, Hung Y, Luo L, Stow JL.   +4 more
europepmc   +1 more source

Regulation of p70 S6 Kinase by Complex Formation between the Rac Guanine Nucleotide Exchange Factor (Rac-GEF) Tiam1 and the Scaffold Spinophilin [PDF]

, 2003
Rachel J. Buchsbaum, Beth A. Connolly, Larry A. Feig   +2 more
openalex   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source