Results 161 to 170 of about 41,746 (257)

Redox‐Active Guanidines

open access: yesChemElectroChem, Volume 13, Issue 12, 17 June 2026.
Redox‐active guanidines, comprising guanidino‐functionalized aromatics (GFAs) and redox‐active urea azines (RAAs), are electron donors and strong Lewis and Brønsted bases that are used in several applications. They act as redox‐active ligands in bistable coordination compounds and as reagents in dehydrogenative coupling reactions and proton‐coupled ...
Hans‐Jörg Himmel
wiley   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

open access: yesChemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke   +5 more
wiley   +1 more source

RBOHC‐Generated ROS Tune MIZ2/GNOM‐Dependent Root Halotropism in Arabidopsis

open access: yes
Plant, Cell &Environment, EarlyView.
Amir Cohen   +4 more
wiley   +1 more source

The Hoechst Dye‐Binding RNA Aptamer Recognizes Its Ligand in a Highly Dynamic Fashion

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
The Hoechst–RNA aptamer binds a tert‐butyl containing derivative of the Hoechst dye. The study presented here shows that the interactions between the RNA and ligand are highly dynamic with the ligand occupying two overlapping binding sites. The interactions are explored using NMR spectroscopy and time‐resolved fluorescence.
Natasha M. Evans   +2 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

open access: yesAdvanced Materials, Volume 38, Issue 34, 17 June 2026.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed   +9 more
wiley   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu   +7 more
wiley   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 698-710, June 2026.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Mitochondrial Genome of the Indo‐Pacific Mesophotic Coral Leptoseris columna (Scleractinia: Agariciidae) Assembled Using PacBio Long‐Read Sequencing

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
The complete mitochondrial genome of Leptoseris columna was assembled using PacBio long read sequencing. ABSTRACT Leptoseris columna, a mesophotic coral species belonging to the family Agariciidae, is distributed throughout the Indo‐Pacific region.
Nomita Rani Adhikary   +2 more
wiley   +1 more source

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