Results 151 to 160 of about 9,354,840 (235)

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Analysis of the structural mechanism of Rho guanine nucleotide exchange factor activation by G alpha 13.

open access: yes, 2005
Analysis of the structural mechanism of Rho guanine nucleotide exchange factor activation by G alpha ...
Barry Steven. Kreutz (7985480)
core   +2 more sources

Dynamic Surface‐Enhanced Raman Scattering Platform With Multiscale Nanostructural Engineering and Programmable Surface Energy for Artificial Intelligence‐Assisted Discrimination of Helicobacter pylori

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
This study develops a dynamic surface‐enhanced Raman scattering (D‐SERS) platform integrating multiscale nanoparticle geometry, quantum dot coupling, surface‐energy programming, and a multilayer perceptron model for AI‐assisted classification. It enables ultrahigh sensitivity, noninvasive detection, and specific Helicobacter pylori identification.
Ming‐Chang Lu   +4 more
wiley   +1 more source

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar   +3 more
wiley   +1 more source

Iron(II) and Copper(II) Ions Modulating Binding Interaction of Sugar‐Based Silatrane With DNA: Analytical and Theoretical Validation

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A new D‐glucamine‐based triazolyl silatrane and its Fe(II)/Cu(II) complexes exhibit metal‐induced modulation of CT‐DNA binding. Experimental and theoretical investigations reveal enhanced binding affinity and conversion from groove binding to a mixed groove‐binding/intercalative interaction. ABSTRACT Research on molecular systems capable of interacting
Gurjaspreet Singh, Pawan, Brij Mohan
wiley   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang   +4 more
wiley   +1 more source

Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska   +5 more
wiley   +1 more source

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 6, Page 475-486, September 2026.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

open access: yesClinical Genetics, Volume 110, Issue 3, Page 389-401, September 2026.
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree   +18 more
wiley   +1 more source

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