Results 141 to 150 of about 104,742 (325)

Guanine nucleotide-binding proteins.

Japanese Journal of Pharmacology, 1989
Toshiaki Katada, Michio Ui
openaire   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Analysis of Z64 genetic code network [PDF]

Network Biology
The genetic code is the set of rules defining how the sequence of nucleotides in DNA or RNA determines the specific amino acid sequence in the synthesis of protein.
Adil Akhtar, Nasrin Irshad Hussain
doaj  

Identification of guanine nucleotide exchange factors that increase Cdc42 activity in primary human endothelial cells [PDF]

, 2019
Nathalie R. Reinhard, Sanne van der Niet, Anna O. Chertkova, Marten Postma, Peter L. Hordijk, Theodorus W. J. Gadella, Joachim Goedhart   +6 more
openalex   +1 more source

Phytoestrogens regulate mRNA and protein levels of guanine nucleotide‐binding protein, beta‐1 subunit (GNB1) in MCF‐7 cells

, 2009
Srivatcha Naragoni, Shireesha Sankella, Kinesha Harris, Wesley Gray   +3 more
openalex   +1 more source

Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility [PDF]

, 2015
Kyungmin Lee, Yuki Kobayashi, Hyunhyo Seo, Ji‐Hye Kwak, Akira Masuda, Chae‐Seok Lim, Hye‐Ryeon Lee, SukJae Joshua Kang, Pojeong Park, Su-Eon Sim, Naomi Kogo, Hiroaki Kawasaki, Bong‐Kiun Kaang, Shigeyoshi Itohara   +13 more
openalex   +1 more source

Discovery of GuaB inhibitors with efficacy against Acinetobacter baumannii infection

mBio
Guanine nucleotides are required for growth and viability of cells due to their structural role in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell division.
Eric M. Kofoed, Ignacio Aliagas, Terry Crawford, Jialin Mao, Seth F. Harris, Min Xu, Shumei Wang, Ping Wu, Fang Ma, Kevin Clark, Jessica Sims, Yiming Xu, Yutian Peng, Elizabeth Skippington, Ying Yang, Janina Reeder, Savita Ubhayakar, Matt Baumgardner, Zhengyin Yan, Jacob Chen, Summer Park, Hua Zhang, Chun-Wan Yen, Maria Lorenzo, Nicholas Skelton, Xiaorong Liang, Liuxi Chen, Bridget Hoag, Chun Sing Li, Zhiguo Liu, John Wai, Xingrong Liu, Jun Liang, Man Wah Tan   +33 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Hypermethylation of PM20D1 Is Associated With Carotid Bifurcation Intima‐Media Thickness in Dominican Republic Families

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Carotid intima‐media thickness (IMT) is a measure of atherosclerosis and a predictor of vascular diseases. Traditional vascular risk factors and genetic variants do not completely explain the variation in carotid IMT.
Nicole D. Dueker, Hongyu Zhao, Hannah Gardener, Sonya S. Kaur, Chuanhui Dong, Digna Cabral, Ralph L. Sacco, Susan H. Blanton, Tatjana Rundek, Liyong Wang   +9 more
doaj   +1 more source