Mutations at position 1122 in the catalytic domain of the mouse ras‐specific guanine nucleotide exchange factor CDC25Mm originate both loss‐of‐function and gain‐of‐function proteins [PDF]
, 1998 Vittorio Carrera +6 more
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Analysis of Z64 genetic code network [PDF]
Network BiologyThe genetic code is the set of rules defining how the sequence of nucleotides in DNA or RNA determines the specific amino acid sequence in the synthesis of protein.
Adil Akhtar, Nasrin Irshad Hussain
doaj
Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase. [PDF]
, 1984 Alfred G. Gilman
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Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Guanine nucleotide is essential and Ca2+ is a modulator in the exocytotic reaction of permeabilized rat mast cells [PDF]
, 1992 T. H. W. Lillie, Bastien D. Gomperts
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The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Discovery of GuaB inhibitors with efficacy against Acinetobacter baumannii infection
mBioGuanine nucleotides are required for growth and viability of cells due to their structural role in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell division.
Eric M. Kofoed +33 more
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Guanine nucleotide exchange factors and colon neoplasia
Frontiers in Cell and Developmental BiologyDespite many diagnostic and therapeutic advances, colorectal cancer (CRC) remains the second leading cause of cancer death for men and women in the United States. Alarmingly, for reasons currently unknown, the demographics of this disease have shifted towards a younger population.
Lea-Pearl Njei +8 more
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Arf6 Guanine Nucleotide Exchange Factor Cytohesin-2 Binds to CCDC120 and Is Transported Along Neurites to Mediate Neurite Growth [PDF]
, 2014 Tomohiro Torii +7 more
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