Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells
Cell Proliferation, EarlyView.The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li +14 more
wiley +1 more source
Multidomain organization of eukaryotic guanine nucleotide exchange translation initiation factor eIF‐2B subunits revealed by analysis of conserved sequence motifs [PDF]
, 1995 Eugene V. Koonin
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Human FASTK preferentially binds single‐stranded and G‐rich RNA
The FEBS Journal, EarlyView.Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain Cytosol in Order to Be in a Low Affinity State for Guanine Nucleotides. [PDF]
J Biol Chem, 2015 Ogita Y +5 more
europepmc +1 more source
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier
The FEBS Journal, EarlyView.Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto +8 more
wiley +1 more source
Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor [PDF]
, 2016 Lydia Chávez‐Vargas +9 more
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Journal of Integrative Plant Biology, EarlyView.Analysis of a near‐complete assembly of the genome of the highly transformable maize inbred line LH244 revealed its high genetic similarity to B73 and will serve as a much‐needed resource for functional genomics and genome editing of maize. ABSTRACT The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and ...
Kaiwen Tan +14 more
wiley +1 more source
Guanine nucleotide directed co-assembly with Pt-complexes for tailoring chiroptical properties and multimodal molecular recognition. [PDF]
Chem SciXiao J +8 more
europepmc +1 more source
SH3‐class Ras guanine nucleotide exchange factors are essential forAspergillus fumigatusinvasive growth [PDF]
, 2019 Adela Martín‐Vicente +4 more
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