Results 191 to 200 of about 99,476 (367)
High-energy guanine nucleotides as a signal capable of linking growth to cellular energy status via the control of gene transcription. [PDF]
Curr Genet, 2019 Hesketh A, Oliver SG.
europepmc +1 more source
Medicine Advances, EarlyView.The CRISPR‐Cas9 system enables targeted genome editing with high precision but is challenged by unintended off‐target effects. In this study, a feedforward neural network (FNN) model was developed to predict on‐target and off‐target events using SITE‐Seq dataset.
Pavithra Nagendran +2 more
wiley +1 more source
The Nature of T-Factor-Guanine Nucleotide Complexes
Cold Spring Harbor Symposia on Quantitative Biology, 1969 S. Hattman +2 more
openaire +3 more sources
Pediatric Discovery, EarlyView.ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang +4 more
wiley +1 more source
Case Studies of Orphan Domain Reclassification in ECOD by Expert Curation
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Homology‐based protein domain classification is a powerful tool for gaining biological insights into protein function. This classification process has been significantly enhanced by the availability of experimental structures and high‐accuracy structural models generated by advanced tools such as AlphaFold.
Jimin Pei +3 more
wiley +1 more source
The association of NADPH with the guanine nucleotide exchange factor from rabbit reticulocytes: a role of pyridine dinucleotides in eukaryotic polypeptide chain initiation. [PDF]
, 1986 J N Dholakia +4 more
openalex +1 more source
The role of selection pressure in shaping zoxamide resistance in Plasmopara viticola populations
Pest Management Science, EarlyView.Zoxamide resistance management in Plasmopara viticola: controlling selection pressure through optimal fungicide application frequency to reduce the spread of resistant strains possessing different point mutations associated with resistance. Abstract BACKGROUND Zoxamide, a β‐tubulin inhibitor, is widely used in vineyards to control downy mildew caused ...
Mattia Peracchi +4 more
wiley +1 more source
Guanine nucleotide-binding protein, alpha i-3, directly activates a cation channel in rat renal inner medullary collecting duct cells. [PDF]
, 1989 Douglas B. Light +2 more
openalex +1 more source
Small, EarlyView.IGA3, a guanine‐rich insulin aptamer, adopts different structures depending on environmental conditions. Under low cation concentrations, IGA3 forms a non‐G‐quadruplex structure that interacts with insulin. This finding highlights that guanine‐rich nucleic acids, in structures other than G‐quadruplex, can also bind to proteins, revealing valuable ...
Naoya Iwano +9 more
wiley +1 more source