Results 81 to 90 of about 150,931 (301)
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
Advanced Science, EarlyView.The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source
EspM2 is a RhoA guanine nucleotide exchange factor [PDF]
Cellular Microbiology, 2010 We investigated how the type III secretion system WxxxE effectors EspM2 of enterohaemorrhagic Escherichia coli, which triggers stress fibre formation, and SifA of Salmonella enterica serovar Typhimurium, which is involved in intracellular survival, modulate Rho GTPases.
Arbeloa, A +7 more
openaire +3 more sources
, 1986 The effect of guanine nucleotides on platelet and calf brain cytosolic phospholipase C was examined in the absence of membranes or detergents in an assay using labeled lipid vesicles. Guanine nucleotides stimulate hydrolysis of [3H]phosphatidylinositol 4,
Deckmyn, Hans, Tu, S.M., Majerus, P.W.
core +1 more source
Guanine nucleotides reduce the free calcium requirement for secretion of granule constituents from permeabilized human neutrophils [PDF]
, 1986 Human neutrophils can be permeabilized with the cholesterol complexing agent digitonin and then induced to secrete lysosomal constituents by increases in free Ca2+ alone.
Smolen, James E., Stoehr, Sally Jo
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Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
Estudo da modulação do transporte sinaptossomal de L-[3H] glutamato por derivados da guanina e seu papel como neurotransmissores [PDF]
, 2005 Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas.
Santos, Tiago Góss dos
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Guanine-Specific Chemical Reaction Reveals ssDNA Interactions on Carbon Nanotube Surfaces
, 2022 Understanding the conformations of physisorbed single-stranded DNA (ssDNA) oligos on single-wall carbon nanotube (SWCNT) surfaces is important for advancing basic nanoscience and for developing applications in biomedicine and quantum information ...
Ali A. Alizadehmojarad +7 more
core +1 more source
Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption
Advanced Science, EarlyView.This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu +7 more
wiley +1 more source
Estudo dos efeitos neuroprotetores e neurotóxicos dos derivados da guanina em fatias de hipocampo de ratos e em culturas de células de neuroblastoma humano SHSY-5Y [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Neurociências, Florianópolis, 2009Avaliação do efeito neuroprotetor de guanosina-5'-monofosfato (GMP) e guanosina frente à ...
Molz, Simone
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, 1983 A B S T R A C T The oligopeptide chemoattractant receptor on human polymorphonuclear leukocyte (PMN) membranes exists in two affinity states. Since guanine nucleotides regulate the binding affinity and transductional activity of several other types of ...
C Koo, R J Lefkowitz, R Snyderman
core +1 more source