Results 91 to 100 of about 201,939 (380)

Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]

, 1992
1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G., Gratzl, Manfred, Rosenthal, W., Spicher, K., Stecher, B., Wegenhorst, U.   +5 more
core  

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]

, 2013
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P, Bader, DL, Chowdhury, TT, Hobbs, AJ, Moyes, AJ, Peake, N, Ramachandran, M, Salter, DM, Su, N   +8 more
core   +2 more sources

Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma

Advanced Science, EarlyView.
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang, Kun Shang, Lidong Gong, Qian Xie, Jianfei Sun, Meng Xu, Xunbin Wei, Zhaoheng Xie, Xinyu Liu, Hao Tang, Zhengren Xu, Wei Wang, Haihua Xiao, Zhiqiang Lin, Hongbin Han   +14 more
wiley   +1 more source

Construction of Supramolecular Organogel with Circularly Polarized Luminescence by Self-Assembled Guanosine Octamer

Cell Reports Physical Science, 2020
Summary: Gel formation using guanosine self-assembly is an important process in supramolecular chemistry. Here, we report the stepwise construction of circularly polarized luminescent supramolecular organogels from self-assembled guanosine quadruplexes ...
Yanbin Zhang, Ying He, Lukasz Wojtas, Xiaodong Shi, Hao Guo   +4 more
doaj  

Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA.

Journal of the American Chemical Society, 2015
The archetypical fluorescent nucleoside analog, 2-aminopurine (2Ap), has been used in countless assays, though it suffers from very low quantum yield, especially when included in double strands, and from the fact that its residual emission frequently ...
M. Sholokh, Rajhans Sharma, Dongwon Shin, R. Das, O. Zaporozhets, Y. Tor, Y. Mély   +6 more
semanticscholar   +1 more source

GTP and Ca2+ Modulate the Inositol 1,4,5-Trisphosphate-Dependent Ca2+ Release in Streptolysin O-Permeabilized Bovine Adrenal Chromaffin Cells [PDF]

, 1991
The inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release was studied using streptolysin O-permeabilized bovine adrenal chromaffin cells. The IP3-induced Ca2+ release was followed by Ca2+ reuptake into intracellular compartments.
Ahnert-Hilger G., Ahnert-Hilger G., B. Stecher, Bhakdi S., Bhakdi S., Brass L. F., Chueh S.-H., Comerford J. G., Danoff S. K., Dawson A. P., Fohr K. J., G. Ahnert-Hilger, Hirata M., Hugo F., J. Scott, Joseph S. K., K. J. Föhr, Kao L.-S., Livett B., M. Gratzl, Rossier M. F., Stoehr S. J., Supattapone S., Worley P. F.   +23 more
core   +1 more source

Fn14 Controls the SIRT2‐Mediated Deacetylation of Slug to Inhibit the Metastasis of Epithelial Ovarian Cancer

Advanced Science, EarlyView.
It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu, Shengze Li, Chunyang Feng, Ruiju He, Ruolan Wu, Zhijun Hu, Jinhua Huang, Wenjing Wang, Lei Huang, Lihua Qiu   +9 more
wiley   +1 more source

Hierarchical Formation of Fibrillar and Lamellar Self-Assemblies from Guanosine-Based Motifs

Journal of Nucleic Acids, 2010
Here we investigate the supramolecular polymerizations of two lipophilic guanosine derivatives in chloroform by light scattering technique and TEM experiments.
Paolo Neviani, Dominique Sarazin, Marc Schmutz, Christian Blanck, Nicolas Giuseppone, Gian Piero Spada   +5 more
doaj   +1 more source

Conformation, hydrogen bonding and aggregate formation of guanosine 5′-monophosphate and guanosine in dimethylsulfoxide [PDF]

Nucleic Acids Research, 1994
The tetrabutylammonium salt of guanosine 5'-monophosphate (5'-GMP) dissolves in DMSO-d6 forming aggregated species which exhibit some properties of reverse micelles. 1H NOESY experiments show that the 5'-GMP adopts the syn conformation about the glycosidic bond.
Judith A. Walmsely, Leoncio A. Garza, William R. Winchester, R. Ted West   +3 more
openaire   +2 more sources

Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.

Proceedings of the National Academy of Sciences of the United States of America, 1977
Nitric oxide gas (NO) increased guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] activity in soluble and particulate preparations from various tissues.
W. Arnold, C. K. Mittal, S. Katsuki, F. Murad   +3 more
semanticscholar   +1 more source