Results 61 to 70 of about 1,634 (145)

A study of bacterial response to polypeptide antibiotics.

, 1983
International audienceWhen Escherichia coli cells are treated with either polymixin or gramicidin at concentrations that block protein and RNA synthesis, they accumulate a significant amount of guanosine tetraphosphate ppGpp.
Cortay, Jc, Cozzone, Aj
core   +2 more sources

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

Water and Environment Journal, Volume 40, Issue 2, Page 183-202, May 2026.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze, Musa Marimani, Katlego Mamabolo, Mrudula Patel   +3 more
wiley   +1 more source

Versatile enzymatic system for the production of guanosine polyphosphates [PDF]

, 2010
During periods of environmental stress, bacteria synthesize guanosine tetraphosphate (ppGpp, magic spot I) and guanosine pentaphosphate (pppGpp, magic spot II) in a process known as the stringent response.
Wang, Y, Watt, RM, Choi, MMY
core  

Table_1_Identification, characterization and expression analysis of wheat RSH family genes under abiotic stress.xlsx

, 2023
Guanosine pentaphosphate and guanosine tetraphosphate are collectively called (p)ppGpp (Guanosine tetraphosphate and pentaphosphate). (p)ppGpp content in plants is affected by conditions such as light, salt, pH, UV light, and environmental phytohormones.
Youning Wang (414944), Xiaowen Han (9615903), Wang Chen (559614), Mengru Wang (603848), Yingxin Zhang (165098), Shuping Wang (466892), Wenli Wang (1701169), Wei Hong (432102)   +7 more
core   +1 more source

Understanding the development of bacterial colony: Physiology, new technology, and modeling

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Bacterial colonies, as dynamic ecosystems, display intricate behaviors and organizational structures that profoundly influence their survival and functionality. These communities engage in physiological and social interactions, resulting in remarkable spatial heterogeneity.
Jingwen Zhu, Pan Chu, Xiongfei Fu
wiley   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

Clavibacter michiganensis Reframed: The Story of How the Genomics Era Made a New Face for an Old Enemy

Molecular Plant Pathology, Volume 26, Issue 5, May 2025.
We provide a historical perspective and an updated overview on the aetiology, epidemiology and management strategies of tomato bacterial canker caused by Clavibacter michiganensis. ABSTRACT Objective Bacterial wilt and canker of tomato caused by the gram‐positive corynebacterial species Clavibacter michiganensis is an economically important disease ...
Ebrahim Osdaghi, Hamid Abachi, Marie‐Agnes Jacques   +2 more
wiley   +1 more source

Guanylate Kinase 1 Deficiency: A Novel and Potentially Treatable Mitochondrial DNA Depletion/Deletions Disease

Annals of Neurology, Volume 96, Issue 6, Page 1209-1224, December 2024.
Objective Mitochondrial DNA (mtDNA) depletion/deletions syndrome (MDDS) comprises a group of diseases caused by primary autosomal defects of mtDNA maintenance. Our objective was to study the etiology of MDDS in 4 patients who lack pathogenic variants in known genetic causes.
Agustin Hidalgo‐Gutierrez, Jonathan Shintaku, Javier Ramon, Eliana Barriocanal‐Casado, Alba Pesini, Russell P. Saneto, Gloria Garrabou, Jose Cesar Milisenda, Ana Matas‐Garcia, Laura Gort, Olatz Ugarteburu, Yue Gu, Lahari Koganti, Tian Wang, Saba Tadesse, Megi Meneri, Monica Sciacco, Shuang Wang, Kurenai Tanji, Marshall S. Horwitz, Michael O. Dorschner, Mahesh Mansukhani, Giacomo Pietro Comi, Dario Ronchi, Ramon Marti, Antonia Ribes, Frederic Tort, Michio Hirano   +27 more
wiley   +1 more source

Guanosine tetraphosphate modulates salicylic acid signalling and the resistance of $Arabidopsis\ thaliana$ to Turnip mosaic virus

, 2017
International audienceChloroplasts can act as key players in the perception and acclimatization of plants to incoming environmental signals. A growing body of evidence indicates that chloroplasts play a critical role in plant immunity.
Hela Abdelkefi, Field, Ben, Sylvie Citerne, Ke, Hang, Robaglia, Christophe, C., Robaglia, Christophe,, Ludivine Soubigou-Taconnat, Mouille, Gregory, Gregory Mouille, Ben Field, Sugliani, Matteo, Citerne, Sylvie, Hang Ke, Hatem Fakhfakh, Christophe Robaglia, Harchouni, Seddik, Fakhfakh, Hatem, Seddik Harchouni, Matteo Sugliani, Abdelkefi, Hela, Soubigou-Taconnat, Ludivine   +20 more
core   +1 more source

Phages produce persisters

Microbial Biotechnology, Volume 17, Issue 8, August 2024.
Bacterial infections are predicted to be the main cause of death by 2050, and persister cells often form during periods of lethal stress. Here, we show phage infections generate persister cells, and these persisters may undermine phage therapy. Abstract Arguably, the greatest threat to bacteria is phages.
Laura Fernández‐García, Joy Kirigo, Daniel Huelgas‐Méndez, Michael J. Benedik, María Tomás, Rodolfo García‐Contreras, Thomas K. Wood   +6 more
wiley   +1 more source