Results 61 to 70 of about 1,579 (116)

Phages produce persisters

Microbial Biotechnology, Volume 17, Issue 8, August 2024.
Bacterial infections are predicted to be the main cause of death by 2050, and persister cells often form during periods of lethal stress. Here, we show phage infections generate persister cells, and these persisters may undermine phage therapy. Abstract Arguably, the greatest threat to bacteria is phages.
Laura Fernández‐García, Joy Kirigo, Daniel Huelgas‐Méndez, Michael J. Benedik, María Tomás, Rodolfo García‐Contreras, Thomas K. Wood   +6 more
wiley   +1 more source

Intracanal microbiome profiles of two apical periodontitis cases in one patient: A comparison with saliva and plaque profiles

Clinical and Experimental Dental Research, Volume 10, Issue 2, April 2024.
Abstract Objectives To determine the characteristics of the endodontic microbiome. Material and Methods Saliva, plaque, and infected root canal wall dentin of two teeth suffering from apical periodontitis were harvested from a 58‐year‐old man. Bacterial DNA was extracted from each sample, and 16S rRNA gene analysis targeting the V3–V4 region was ...
Keiko Yamaki, Toru Tamahara, Jumpei Washio, Takuichi Sato, Ritsuko Shimizu, Satoru Yamada   +5 more
wiley   +1 more source

Sound the (Smaller) Alarm: The Triphosphate Magic Spot Nucleotide pGpp. [PDF]

Infect Immun, 2023
Malik A, Hept MA, Purcell EB.
europepmc   +1 more source

Determining the Importance of the Stringent Response for Methicillin-Resistant Staphylococcus aureus Virulence In Vivo. [PDF]

J Infect Dis
Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA, Corrigan RM.   +5 more
europepmc   +1 more source

Clinical Rel mutations that increase basal (p)ppGpp promote conjugal transfer of staphylococcal resistance plasmids. [PDF]

Microbiology (Reading)
Deventer AT, Sutherland A, Biernacka D, Johnston PR, Stevens CE, Kaczorowska AK, Boraston AB, Hobbs JK.   +7 more
europepmc   +1 more source

Mike Cashel: magic spot magician. [PDF]

J Bacteriol
Hinton DM, Gottesman S.
europepmc   +1 more source

Studies on extracellular ATP: nucleotide pyrophosphotransferase from Streptomyces adephospholyticus. IV. Structure and some properties of the new nucleotides (adenosine pentaphosphate, guanosine tetraphosphate and inosine pentaphosphate) synthesized by nucleotide pyrophosphotransferase.

Agricultural and Biological Chemistry, 1975
HAMAGISHI, Yasutaro, NISHINO, Toyokazu, MURAO, Sawao   +2 more
openaire   +2 more sources

<i>Salmonella</i> Persistence in Infection: Molecular Regulation, Host Microenvironments, and Multiscale Heterogeneity. [PDF]

Microorganisms
Ding D, Sun H, Yang J.
europepmc   +1 more source

Inhibition of Contractility of Isolated Caprine Detrusor by the Rho Kinase Inhibitor Fasudil and Reversal by the Guanylyl Cyclase Inhibitor ODQ. [PDF]

Curr Ther Res Clin Exp
Jeeviha NJ, Kumar A, Mathew RA, Joseph S, Haris M, Shanthi M, Peedicayil J.   +6 more
europepmc   +1 more source

Targeting the bacterial stringent response to combat human pathogens. [PDF]

Front Immunol
Gąsior F, Bryszkowska K, Klasa W, Potrykus K.   +3 more
europepmc   +1 more source