Results 51 to 60 of about 1,579 (116)
Synthesis of Guanosine Tetra- and Pentaphosphate Requires the Presence of a Codon-Specific, Uncharged Transfer Ribonucleic Acid in the Acceptor Site of Ribosomes [PDF]
Proceedings of the National Academy of Sciences, 1973 The nucleotides ppGpp and pppGpp accumulate when wild-type, but not rel - , strains of Escherichia coli are starved for required amino acids. These compounds are synthesized on ribosomes, in the presence of the product of the
W A, Haseltine, R, Block
openaire +2 more sources
Brazilian Archives of Biology and Technology, 2013 Catharacta maccormicki blood samples were collected in the winter (October) and in the summer (February) in order to study the intraerythrocytic organic phosphates, hemoglobin (Hb) electrophoretic patterns, oxygen blood equilibrium and stripped Hbs, as ...
Gustavo Fraga Landini +4 more
doaj +1 more source
A New Transfer RNA Fragment Reaction: TpΨpCpGp Bound to a Ribosome-Messenger RNA Complex Induces the Synthesis of Guanosine Tetra- and Pentaphosphates [PDF]
Proceedings of the National Academy of Sciences, 1974 The tetranucleotide TpΨpCpGp, when bound to Escherichia coli 50S ribosomal subunits, can replace intact tRNA in the stringent factor-directed synthesis of guanosine tetra- and pentaphosphates.
D, Richter, V A, Erdmann, M, Sprinzl
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De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
Proteomic Analysis of Lactococcus lactis FM03 Under Prolonged Alkaline Stress
Environmental Microbiology, Volume 28, Issue 7, July 2026.Overview of alkaline resistance mechanisms in Lactococcus lactis FM03. Sustained growth at pH 8 triggers extensive physiological remodelling, including activation of general stress response proteins, suppression of acid resistance, elevated amino acid production, altered cell wall biosynthesis, and doubling of the cell wall thickness.
Tamara A. L. Bendig +4 more
wiley +1 more source
Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments
Water and Environment Journal, Volume 40, Issue 2, Page 183-202, May 2026.Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze +3 more
wiley +1 more source
Understanding the development of bacterial colony: Physiology, new technology, and modeling
Quantitative Biology, Volume 13, Issue 4, December 2025.Abstract Bacterial colonies, as dynamic ecosystems, display intricate behaviors and organizational structures that profoundly influence their survival and functionality. These communities engage in physiological and social interactions, resulting in remarkable spatial heterogeneity.
Jingwen Zhu, Pan Chu, Xiongfei Fu
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Molecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens +5 more
wiley +1 more source
Molecular Plant Pathology, Volume 26, Issue 5, May 2025.We provide a historical perspective and an updated overview on the aetiology, epidemiology and management strategies of tomato bacterial canker caused by Clavibacter michiganensis. ABSTRACT Objective Bacterial wilt and canker of tomato caused by the gram‐positive corynebacterial species Clavibacter michiganensis is an economically important disease ...
Ebrahim Osdaghi +2 more
wiley +1 more source
Annals of Neurology, Volume 96, Issue 6, Page 1209-1224, December 2024.Objective Mitochondrial DNA (mtDNA) depletion/deletions syndrome (MDDS) comprises a group of diseases caused by primary autosomal defects of mtDNA maintenance. Our objective was to study the etiology of MDDS in 4 patients who lack pathogenic variants in known genetic causes.
Agustin Hidalgo‐Gutierrez +27 more
wiley +1 more source