Results 41 to 50 of about 1,634 (145)
Frontiers in Cellular and Infection Microbiology, 2022 Antimicrobial resistance (AMR) in bacteria is an important global health problem affecting humans, animals, and the environment. AMR is considered as one of the major components in the “global one health”.
Thandavarayan Ramamurthy +6 more
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LD‐transpeptidases: the great unknown among the peptidoglycan cross‐linkers
The FEBS Journal, Volume 289, Issue 16, Page 4718-4730, August 2022., 2022 Peptidoglycan cross‐linking enzymes LD‐transpeptidases (LDTs) have kept an aura of mystery for a long time. However, a number of recent reports have linked the activity of LDTs to cell wall adaptation to stress including β‐lactam antibiotics, outer membrane stability, and toxin delivery.
Alena Aliashkevich, Felipe Cava
wiley +1 more source
Microbiology Spectrum, 2023 Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a serious public health threat. We recently demonstrated that the presence of a novel prophage ϕSA169 was associated with vancomycin (VAN) treatment failure ...
Yi Li +9 more
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Letters in Applied Microbiology, Volume 74, Issue 5, Page 820-830, May 2022., 2022 Significance and Impact of the Study: Gram‐negative bacteria secrete outer membrane vesicles (OMVs) with immunostimulatory properties and proteoliposome nanostructures, making it highly immunogenic for protein delivery. The fusion of heterologous antigen to cytolysin A (clyA) has proven to direct protein translocation into periplasmic space and ...
F.‐K. Loh +3 more
wiley +1 more source
Bio-Protocol, 2016 The stringent response in bacteria is a stress response that is mediated by the signaling molecules guanosine tetraphosphate and pentaphosphate [(p)ppGpp], alarmones that are also directly related to virulence. Therefore, determination of (p)ppGpp levels
Smitha Sivapragasam, Anne Grove
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Synthesis of guanosine tetra- and pentaphosphates by the obligately anaerobic bacterium Bacteroides thetaiotaomicron in response to molecular oxygen [PDF]
Journal of Bacteriology, 1979 Guanosine 5'-diphosphate 3'-diphosphate (ppGpp) and guanosine 5'-triphosphate 3'-diphosphate (pppGpp) were detected in formic acid extracts of air-exposed culutres of Bacteroides thetaiotaomicron. The identification of ppGpp and pppGpp in B. thetaiotaomicron was based on the following results: (i) cochromatography of 32P-labeled hyperphosphorylated ...
T L, Glass +3 more
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SpoT Induces Intracellular
mBio, 2020 Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion ...
Liam F. Fitzsimmons +8 more
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A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]
, 1988 A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
Soll, Jürgen +2 more
core +1 more source
Studies on the Control of Development. Accumulation of Guanosine Tetraphosphate and Pentaphosphate in Response to Inhibition of Protein Synthesis in Bacillus subtilis [PDF]
European Journal of Biochemistry, 1975 Bacillus subtilis cells accumulate unusual phosphorylated substances at the end of logarithmic growth in a semi-synthetic medium. Two of these substances are guanosine 3'(2')-diphosphate 5'-diphosphate (ppGpp) and guanosine 3'(2')-diphosphate 5'-triohosphate (pppGpp) which, in contrast to amino-acid-starved Escherichia coli cells, are not degraded in ...
H J, Rhaese, H, Dichtelmüller, R, Grade
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BMC Genomics, 2020 Background The nucleotide second messengers, i.e., guanosine tetraphosphate and pentaphosphate [collectively referred to as (p) ppGpp], trigger the stringent response under nutrient starvation conditions and play an essential role in virulence in the ...
Ho-wen Yang +4 more
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