Results 111 to 120 of about 39,412 (236)
Journal of Diabetes Investigation, EarlyView.SGLT2 inhibitor use at discharge was associated with a reduced risk of heart failure readmission in elderly patients with diabetes, with no significant differences among individual agents. ABSTRACT Aims To evaluate the effect of sodium–glucose cotransporter 2 inhibitor (SGLT2i) administration at hospital discharge on heart failure (HF) readmission ...
Kazuya Hiura +3 more
wiley +1 more source
Modulation of swimming in the gastropod Melibe leonina by nitric oxide [PDF]
, 2002 Nitric oxide (NO) is a gaseous intercellular messenger produced by the enzyme nitric oxide synthase. It has been implicated as a neuromodulator in several groups of animals, including gastropods, crustaceans and mammals.
Newcomb, James M. +1 more
core +1 more source
Natriuretic peptide receptors on rat thymocytes: Inhibition of proliferation by atrial natriuretic peptide. [PDF]
, 1996 Because the thymus expresses the natriuretic peptides (NP) as well as their respective receptors, an involvement of NP in the physiology of this organ has been suggested.
Schmidt, Karin-Nicole +2 more
core +1 more source
Neurogastroenterology &Motility, EarlyView.Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase +7 more
wiley +1 more source
Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension
European Respiratory Review, 2015 Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but life-threatening disease resulting from unresolved thromboembolic obstructions.
Marius M. Hoeper
doaj +1 more source
GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress [PDF]
, 2017 Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium.
Kraft, Crystal +5 more
core +2 more sources
The therapeutic role of exercise training during menopause for reducing vascular disease
Experimental Physiology, EarlyView.Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing +4 more
wiley +1 more source
Haematologica, 2008 Increased leukocyte adhesion to vascular endothelium contributes to vaso-occlusion in sickle cell disease. Since nitric oxide bioavailability is decreased in sickle cell disease and nitric oxide may inhibit leukocyte adhesion, we investigated whether ...
Andreia A. Canalli +4 more
doaj +1 more source
Comprehensive Physiology, Volume 16, Issue 3, June 2026.Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid +5 more
wiley +1 more source
Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels [PDF]
, 2001 Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and ...
A Dietz +22 more
core +1 more source