Disruption of Hepatic Sinusoidal Homeostasis Leads to Hepatopulmonary Syndrome
Journal of Cellular and Molecular Medicine, Volume 29, Issue 9, May 2025.ABSTRACT Hepatopulmonary syndrome (HPS) is a pulmonary vascular complication of liver disease and/or portal hypertension. HPS manifests as impaired gas exchange and hypoxemia due to intrapulmonary vascular dilatations and shunts. In response to primary liver disease, the abnormal adaptation of respiratory epithelial cells, pulmonary endothelial cells ...
Jiaxin Chen +7 more
wiley +1 more source
Equivalence of background and bleaching desensitization in isolated rod photoreceptors of the larval tiger salamander. [PDF]
, 1996 Psychophysical experiments have shown an equivalence between sensitivity reduction by background light and by bleaches for the human scotopic system.
Cornwall, MC, Fain, GL, Jones, GJ
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ROS-GC interlocked Ca2+-sensor S100B protein signaling in cone photoreceptors: review [PDF]
, 2014 Photoreceptor rod outer segment membrane guanylate cyclase (ROS-GC) is central to visual transduction; it generates cyclic GMP, the second messenger of the photon signal.
Duda, Teresa +3 more
core +2 more sources
Guanyl cyclase in a mammalian photoreceptor [PDF]
FEBS Letters, 1973 Christo Goridis +3 more
openaire +3 more sources
Repurposing Riociguat for Treatment of Refractory Angina Resulting From Coronary Spasm
JACC: Case Reports, 2021 Coronary spasm is a frequent cause of angina despite unobstructed coronary arteries, and symptom control with recommended drugs is limited. We report the case of a 77-year-old woman who had refractory angina despite conventional antianginal treatment ...
Valeria Martínez Pereyra, MS +8 more
doaj
APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. [PDF]
, 2020 Sporadic colorectal cancer initiates with mutations in APC or its degradation target β-catenin, producing TCF-dependent nuclear transcription driving tumorigenesis. The intestinal epithelial receptor, GUCY2C, with its canonical paracrine hormone guanylin,
Bashir, Babar +7 more
core +1 more source
SGLT‐2 inhibitors for cardiac amyloidosis: Hype or hope?
European Journal of Clinical Investigation, EarlyView.
Flavio Tangianu +3 more
wiley +1 more source
Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension
European Respiratory Review, 2015 Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but life-threatening disease resulting from unresolved thromboembolic obstructions.
Marius M. Hoeper
doaj +1 more source
Properties of particulate, membrane-associated and soluble guanylate cyclase from cardiac muscle, skeletal muscle, cerebral cortex and liver [PDF]
, 1976 Susan J. Sulakhe +2 more
openalex +1 more source
Factors Affecting the Activity of Guanylate Cyclase in Lysates of Human Blood Platelets [PDF]
, 1979 The mechanism by which physiological stimuli increase cyclic GMP formation in platelets or in other cells is unknown. Agents that promote the formation of cyclic GMP in intact cells have in general not been found to stimulate the activity of guanylate ...
Brotherton, Fontaine Adams Abigail
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