Results 91 to 100 of about 1,921,356 (283)

Endogenous jaw bone regeneration: past, present, and future

open access: yesMedical Review
Jaw bone defects impair oral function and facial aesthetics, reducing patients’ quality of life. While significant progress has been achieved in systemic skeletal repair, jaw bone regeneration remains challenging due to its distinct biological and ...
Xu Zhuoran, Zhang Wenjie
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials [PDF]

open access: yes, 2015
The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone formation in bone defects and the ...
Elgali, Ibrahim
core   +1 more source

Aligned Nanofiber-Guided Bone Regeneration Barrier Incorporated with Equine Bone-Derived Hydroxyapatite for Alveolar Bone Regeneration

open access: yes, 2020
Post-surgery failure of dental implants due to alveolar bone loss is currently critical, disturbing the quality of life of senior dental patients. To overcome this problem, bioceramic or bone graft material is loaded into the defect.
Jong Chung   +9 more
core   +2 more sources

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

open access: yes, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam   +11 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Guided bone regeneration: new advances in the treatment of bone defects

open access: yesRevista Cubana de Estomatología, 2014
Introduction: the procedure of guided bone regeneration has proven to be a successful technique to promote the filling of bone defects and enlarge the dimensions of atrophic alveolar ridges prior to conventional or implant-supported prosthetic ...
Verónica Gómez Arcila   +4 more
doaj  

Multifunctional Nanofibrous Hollow Microspheres for Enhanced Periodontal Bone Regeneration

open access: yesAdvanced Science
Destructive periodontitis destroys alveolar bone and eventually leads to tooth loss. While guided bone regeneration, which is based on creating a physical barrier to hinder the infiltration of epithelial and connective tissues into defect sites, has been
Qian Li, Chi Ma, Yan Jing, Xiaohua Liu
doaj   +1 more source

Combination of a Synthetic Bioceramic Associated with a Polydioxanone-Based Membrane as an Alternative to Autogenous Bone Grafting

open access: yesBiomimetics
The purpose of this study was to evaluate the repair process in rat calvaria filled with synthetic biphasic bioceramics (Plenum® Osshp-70:30, HA:βTCP) or autogenous bone, covered with a polydioxanone membrane (PDO).
Paula Buzo Frigério   +6 more
doaj   +1 more source

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