Results 81 to 90 of about 2,076,884 (287)

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

Exploring Magnesium Membranes as a Promising Alternative in Guided Bone Regeneration: A Literature Review.

Albanian Journal of Trauma and Emergency Surgery
Introduction: Alveolar ridge atrophy is an unavoidable consequence of tooth extraction, often resulting in Bone defects complicating ideal implant placement are a significant concern.
Amela Muça, Alba Koshovari, Leart Berdica, Teona Bushati, Ardita Koçi, Silvana Bara, Klaudia Lika   +6 more
doaj   +1 more source

Platelet-rich fibrin application in immediate implant placement

Journal of International Clinical Dental Research Organization, 2017
The dental rehabilitation of a patient following single-tooth extraction in the esthetic zone is often clinically challenging. The treatment option for this is implant-supported single crown which has the advantage that adjacent teeth do not have to be ...
Vijayalakshmi Rajaram, Ramakrishnan Theyagarajan, Jaideep Mahendra, Ambalavanan Namachivayam, Svedha Priyadharshini   +4 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Clinical application of resorbable polymers in guided bone regeneration

, 2007
Guided bone regeneration was shown to be successful in vitro and in vivo using resorbable or nonresorbable materials. Resorbable material has the advantage of progressive substitution by bone.
Gogolewski, S, Ip, WY
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Guided osteoporotic bone regeneration with composite scaffolds of mineralized ECM/heparin membrane loaded with BMP2-related peptide

, 2018
Tingfang Sun,1,* Man Liu,2,* Sheng Yao,1 Yanhui Ji,1 Lei Shi,3 Kai Tang,1 Zekang Xiong,1 Fan Yang,1 Kaifang Chen,1 Xiaodong Guo1 1Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan ...
Tang K, Guo XD, Shi L, Sun TF, Ji YH, Liu M, Chen KF, Xiong ZK, Yao S, Yang F   +9 more
core  

Histologic Analysis of Alveolar Bone Following Guided Bone Regeneration

, 2004
Background: Questions on new bone quality following guided bone regeneration (GBR) with various graft materials and its importance in osseointegration have been raised.
Ersanli, S, Leblebicioglu, B, S. Ersanli, Olgac, V, V. Olgac, B. Leblebicioglu   +5 more
core   +1 more source

Photobiomodulation and Inorganic Bovine Bone in Guided Bone Regeneration: Histomorphometric Analysis in Rats

, 2023
The objective of this study was to evaluate the efficacy of photobiomodulation in the bone regeneration of critical-sized defects (CSD) filled with inorganic bovine bone associated or not with collagen membranes.
Michyele Cristhiane Sbrana, Luísa Belluco Guerrini, Ana Lúcia Pompéia Fraga de Almeida, Caroline Chepernate Vieira dos Santos, Nicole Rosa de Freitas, Luis Augusto Esper   +5 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source