Results 161 to 170 of about 2,076,884 (287)

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen   +10 more
wiley   +1 more source

Distinct healing dynamics associated with xenograft selection in guided bone regeneration. [PDF]

open access: yesSci Rep
de Sousa YMG   +7 more
europepmc   +1 more source

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

open access: yesAdvanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen   +10 more
wiley   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao   +8 more
wiley   +1 more source

Design and applications of barrier membranes for guided bone regeneration. [PDF]

open access: yesBioact Mater
Liu Y, Zhang H, Zhang L, Han J, Yang J.
europepmc   +1 more source

Non‐Canonical Function of DDX21 in Fetal Hematopoiesis Antagonizes KDM5A‐Mediated Repression of Ribosomal and Hematopoietic Genes

open access: yesAdvanced Science, EarlyView.
This study demonstrates a mechanism by which RNA helicase DDX21 coordinates the transcription of hematopoietic and ribosomal genes by interacting with the H3K4me3 demethylase KDM5A. The DDX21‐KDM5A complex co‐occupies active genes in hematopoietic progenitors, thereby ensuring their rapid proliferation during fetal hematopoiesis.
Adrian On‐Wah Leung   +12 more
wiley   +1 more source

Development and Characterization of a Dual Nanofibrillar Membrane of Polylactic Acid Loaded with Hydroxyapatite and Chlorhexidine for Guided Bone Regeneration. [PDF]

open access: yesPolymers (Basel)
Sauma JR   +6 more
europepmc   +1 more source

Electrospun collagen and chitosan-PLLA membrane for guided bone regeneration

open access: yes, 2018
The fabrication of collagen electrospun chitosan-PLLA membranes for guided bone regeneration (GBR) by electrostatic fiber spinning was studied. Fibrous meshes of collagen eletrospun chitosan PLLA membranes were composed of collagen nanofibers and ...
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