Results 81 to 90 of about 98,116 (312)

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Structured implementation of digital, systematically updated guideline recommendations for enhanced adherence in schizophrenia (SISYPHOS)—protocol of a cluster-randomized trial [PDF]

, 2022
Carolin Lorenz, Gabriele Gaigl, Duygu Güler, Theresa Halms, Naiiri Khorikian–Ghazari, Astrid Röh, Marco Schneider, Elias Wagner, Neil Thomas, Angelika Kapfhammer, Marisa Flick, Charline Pielenz, Eva Salveridou‐Hof, Peter Falkai, Wolfgang Gäebel, Alkomiet Hasan, Stefan Leucht   +16 more
openalex   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Adherence to the Kidney Disease: Improving Global Outcomes CKD Guideline in Nephrology Practice Across Countries [PDF]

, 2020
Bénédicte Stengel, Daniel G. Muenz, Charlotte Tu, Élodie Speyer, Natália Alencar de Pinho, Christian Combe, Kunihiro Yamagata, Helmut Reichel, Danilo Fliser, Ziad A. Massy, Antonio Lopes, Michel Jadoul, Wolfgang C. Winkelmayer­, Ronald L. Pisoni, Bruce Robinson, Roberto Pecoits‐Filho, Antonio Lopes, Roberto Pecoits‐Filho, Christian Combe, Christian Jacquelinet, Ziad A. Massy, Bénédicte Stengel, Johannes Duttlinger, Danilo Fliser, Gerhard Lonnemann, Helmut Reichel, Takashi Wada, Kunihiro Yamagata, R. Pisoni, Bruce Robinson, Viviane Cálice-Silva, Ricardo Sesso, Élodie Speyer, Koichi Asahi, Junichi Hoshino, Ichiei Narita, Rachel Perlman, Friedrich K. Port, Nidhi Sukul, Michelle Wong, Eric W. Young, Jarcy Zee   +41 more
openalex   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Adherence to breast cancer guidelines is associated with better survival outcomes: a systematic review and meta-analysis of observational studies in EU countries

BMC Health Services Research, 2020
Background Breast cancer (BC) clinical guidelines offer evidence-based recommendations to improve quality of healthcare for patients with or at risk of BC.
Ignacio Ricci-Cabello, Adrián Vásquez-Mejía, Carlos Canelo-Aybar, Ena Niño de Guzman, Javier Pérez-Bracchiglione, Montserrat Rabassa, David Rigau, Ivan Solà, Yang Song, Luciana Neamtiu, Elena Parmelli, Zuleika Saz-Parkinson, Pablo Alonso-Coello   +12 more
doaj   +1 more source

Guideline Adherence and Hearing Outcomes of Sudden Sensorineural Hearing Loss in the Military Health System [PDF]

, 2020
Charlotte K. Hughes, Matthew Ryan, Jason Adams, Carlos Esquivel   +3 more
openalex   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

Adherence to Integrated Management of Childhood Illnesses Guideline in Treating South Sudanese Children with Cough or Difficulty in Breathing

International Journal of Pediatrics, 2017
Background. Pneumonia substantially kills children aged 2–59 months in South Sudan. However, information on health workers adherence to Integrated Management of Childhood Illnesses (IMCI) guideline in treating children with cough/difficulty in breathing ...
Jonathan Izudi, Stanley Anyigu, David Ndungutse   +2 more
doaj   +1 more source