Results 111 to 120 of about 7,672,395 (400)

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

open access: yesCirculation, 2014
Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk S50 The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular diseases (CVD); improve the management of people
D. Goff   +32 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Association between quality of clinical practice guidelines and citations given to their references [PDF]

open access: yesarXiv, 2013
It has been suggested that bibliometric analysis of different document types may reveal new aspects of research performance. In medical research a number of study types play different roles in the research process and it has been shown, that the evidence-level of study types is associated with varying citation rates.
arxiv  

Software Design Guidelines for Usability [PDF]

open access: yes, 2011
For years, the Human Computer Interaction (HCI) community has crafted usability guidelines that clearly define what characteristics a software system should have in order to be easy to use.
Carvajal García, Laura Elena   +1 more
core   +1 more source

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments.

open access: yesClinical Chemistry, 2009
BACKGROUND Currently, a lack of consensus exists on how best to perform and interpret quantitative real-time PCR (qPCR) experiments. The problem is exacerbated by a lack of sufficient experimental detail in many publications, which impedes a reader's ...
S. Bustin   +11 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Promoviendo el cuidado basado en la evidencia a través de conjuntos de órdenes de Enfermería / Promoting Evidence-Based Care through Nursing Order Sets / Promover o cuidado da saúde baseada em evidências através de conjuntos de critérios de Enfermagem

open access: yesMedUNAB, 2015
Introducción: El uso de las guías de mejores prácticas promueve cuidado basado en la evidencia y calidad en los resultados sanitarios. Tradicionalmente, las guías de mejores prácticas fueron diseñadas para ser usadas como un recurso escrito de forma ...
Rita Wilson. RN., M Ed., MN.   +2 more
doaj  

Guidelines for Comprehensive Fiscal Sponsorship [PDF]

open access: yes, 2010
This paper offers administrative, financial, and legal best practices for fiscal sponsorship arrangements; it was developed by a subgroup of fiscal sponsors practicing comprehensive fiscal sponsorship, many of whom work with the mission of advancing ...

core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Rationing cancer treatment: a qualitative study of perceptions of legitimate limit-setting

open access: yesBMC Health Services Research, 2018
Background Governments are facing tough choices about whether to fund new, promising but highly expensive drugs within the public healthcare system. Decisions that some drugs are not sufficiently beneficial relative to their cost to merit public funding ...
Eli Feiring, Hege Wang
doaj   +1 more source

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