Results 161 to 170 of about 360,883 (358)

Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni   +9 more
wiley   +1 more source

EXPERIMENTAL SCURVY OF THE GUINEA PIG IN RELATION TO THE DIET

open access: hybrid, 1918
Barnett Cohen, Lafayette B. Mendel
openalex   +1 more source

Effects of the P2RX4 antagonist BR11595 in a guinea pig model of chronic asthma

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asthma is characterized by airway hyperresponsiveness (AHR), allergic inflammation, and airway remodelling. Although recent studies have shown that asthma pathophysiology involves P2X4 receptor activation, a potential link with chronic asthma remains to be explored.
Dan Li   +13 more
wiley   +1 more source

Contribution of chloride channels to the action potential and contraction in human myometrium during labour

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose The action potential underpinning calcium delivery for contraction in human uterine smooth muscle (myometrium) consists of an initial spike(s) followed by a prolonged plateau of depolarization to ⁓ −25 mV. The plateau duration establishes contraction duration, especially important in labour.
Helena C. Parkington   +6 more
wiley   +1 more source

Differential expression of a unique protein by intracellular Mycobacterium tuberculosis complex [PDF]

open access: yes, 2001
We have investigated the changes in the protein synthesis pattern in guinea pig peritoneal macrophages following infection with virulent Mycobacterium tuberculosis H37Rv in vitro. By 35S methionine labelling of the newly synthesized proteins followed
Narayanan, P R   +2 more
core  

Plasticity in climate change responses

open access: yesBiological Reviews, EarlyView.
ABSTRACT Recent research has shown that climate change can both induce and modulate the expression of plastic traits but our understanding of the role of phenotypic plasticity as an adaptive response to climate change is limited. In this review, we dissect the mechanisms and impact of phenotypic plasticity as a response to accumulating climatic ...
Angelika Stollewerk   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy