Results 161 to 170 of about 374,362 (351)

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

HAEMOLYTIC STREPTOCOCCOSIS OF GUINEA-PIGS : V. RELATIONSHIP OF BACTERIA AND HOST ANIMAL

, 1960
Kiyoshi Imaizumi, Toshio Tanaka, Shogo Ito, Yoshio Tajima, Akihiro IMAI   +4 more
openalex   +2 more sources

Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder

Children &Society, EarlyView.
Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka, Jodie Copley, Catherine McBryde, Pamela J. Meredith, Natasha Reid   +4 more
wiley   +1 more source

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate–H3K18la–SLC7A11 Axis Explored via Endometrial Organoid and Blastoid–Endometrial Cell Implantation Models

Cell Proliferation, EarlyView.
Clinical samples first revealed impaired lactate synthesis in RIF patients. Subsequently, using endometrial organoids and a blastoid‐endometrial cell implantation model, we demonstrated that lactate enhances endometrial receptivity via H3K18la‐mediated SLC7A11 activation.
Lingling Dong, Xiaobin Sun, Shiyu An, Jinfeng Xiang, Lingmin Hu, Dan Yao, Jiaqian Chang, Ruizhe Jia, Yang Yang, Shuxian Wang   +9 more
wiley   +1 more source

Innervation of sympathetic neurones in the guinea‐pig thoracic chain.

, 1980
Jeff W. Lichtman, Dale Purves, Joseph W. Yip   +2 more
openalex   +2 more sources

Adaptation of guinea‐pig vagal airway afferent neurones to mechanical stimulation [PDF]

, 1999
M. Allen McAlexander, Allen C. Myers, Bradley J. Undem   +2 more
openalex   +1 more source

Social Drivers of Vocal Flexibility in Female Baboons

Ethology, EarlyView.
Female olive baboons selectively grunt when encountering females with dependent offspring. Grunting likelihood depends on rank differences and the strength of their social bond. This study adds to the evidence that nonhuman primates have evolved to use structurally‐inflexible vocalisations in population and context‐flexible ways.
Yaëlle Bouquet, Eloïse C. Déaux, Jessica M. Rothman, Klaus Zuberbühler   +3 more
wiley   +1 more source

Out‐of‐equilibrium pH transients in the guinea‐pig ventricular myocyte [PDF]

, 1998
Chae Hun Leem, Richard D. Vaughan‐Jones   +1 more
openalex   +1 more source

(No) Pets on University Campuses: ‘Animaling’ Citizenship for Pet‐Friendly Spaces

The Geographical Journal, EarlyView.
Short Abstract Rising support for pet‐friendly university campuses is driven largely by assumed human well‐being benefits, even though staff and, to a lesser extent, students, raise concerns about how companion animals can be active participants in campus life.
Clare Holdsworth, Daniel Allen, Mark Lucherini, Cameron Causer   +3 more
wiley   +1 more source