Results 181 to 190 of about 144,138 (264)

Three-Month Administration of PB125 Modifies Histopathology, Redox Homeostasis, and Mobility in the Hartley Guinea Pig Model of Primary Osteoarthritis. [PDF]

Antioxidants (Basel)
Andrie KM, Musci RV, Walsh MA, Bork S, Valenti ZJ, Sanford J, Campbell M, F Afzali L, Afzali MF, Hamilton KL, Santangelo KS.   +10 more
europepmc   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Coexistence of Rete Ovarii Cysts and Cystic Endometrial Hyperplasia in a Guinea Pig (Cavia porcellus)-A Detailed Clinical Case Report. [PDF]

Vet Sci
García-González M, Valiño-Cultelli V, Fernández-Martín S, Vila-Pastor M, González-Cantalapiedra A.   +4 more
europepmc   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

Physiological and immunological aspects of asthma: the guinea pig (Cavia porcellus) as a model of allergic asthma. [PDF]

Lab Anim Res
Pacheco-Alba I, Alvarez-González M.
europepmc   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

Functional and biochemical protection by combined N-acetylcysteine and D-methionine in guinea pig noise-induced hearing loss. [PDF]

Head Face Med
Wu PH, Cheng N, Lo WC, Chang CM, Cheng PW, Liu SH.   +5 more
europepmc   +1 more source

Regional electrical differences and arrhythmia in the rat atria: Role of sympathetic nerve distribution and function

The Journal of Physiology, EarlyView.
Abstract figure legend Atrial fibrillation commonly develops in the left atrium and pulmonary veins (PVs), and can be triggered by sympathetic nerve activity. Here, we examined regional atrial differences in sympathetic nerve distribution and function in the rat.
James Saleeb‐Mousa, Manish Kalla, Neil Herring, Christopher O'Shea, Andrew M. Coney, Keith L. Brain, Andrew P. Holmes   +6 more
wiley   +1 more source

Architecture of the cardiac transverse–axial tubular system across different mammalian species

The Journal of Physiology, EarlyView.
Abstract figure legend Mammalian species differ in ventricular TATS architecture, and cytoplasmic distance to the nearest TATS element covaries with lifespan, body mass, and resting heart rate. Abstract Cardiac excitation–contraction coupling relies on a pancellular network of regular cardiomyocyte surface membrane invaginations, termed the transverse ...
Joachim Greiner, Frédéric Sonak, Wesley Dean Jones, Patricia Morais Costa, Josef Madl, Kathrine Albertine Ryeng, Igor R. Efimov, Zafar Iqbal, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +10 more
wiley   +1 more source

Reassessment of mechanical restitution in guinea pig cardiomyocytes through refined computational modelling. [PDF]

Sci Rep
Pásek M, Nováková M.
europepmc   +1 more source