Results 181 to 190 of about 135,352 (264)

Young Adult Microglial Deletion of C1q Reduces Engulfment of Synapses and Partially Mitigates Cognitive Impairment in an Aggressive Alzheimer's Disease Mouse Model

open access: yesGlia, Volume 74, Issue 9, September 2026.
Young adult deletion of microglial C1q reduced engulfment of Vglut1+ synapses and mitigated spatial cognitive deficits at 10 months of age in the amyloidopathy Arctic mouse model of AD. Neither fibrillar amyloid plaques nor soluble or insoluble Aβ levels in the hippocampus were affected by young adult microglial loss of C1q despite reduced phagocytosis
Tiffany J. Petrisko   +4 more
wiley   +1 more source

Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes

open access: yesGlia, Volume 74, Issue 9, September 2026.
Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani   +5 more
wiley   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

open access: yesGlia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans   +39 more
wiley   +1 more source

An Update on the Model of Connectivity of the Hippocampal Formation (I): The Perforant Pathway to the Dentate Gyrus

open access: yesHippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT The hippocampus participates in crucial functions such as memory consolidation, spatial processing and emotional regulation that require diverse input from multiple cortical areas that is funneled through the upper layers of the entorhinal cortex (EC), mostly from layer II to the dentate gyrus (DG).
Jon I. Arellano, Pasko Rakic
wiley   +1 more source

Psychological Safety, Medical Trauma and Adaptive Functioning in Long‐Term Conditions: A Multidisciplinary Integrative Approach

open access: yesMultiPsych, Volume 1, Issue 3, September 2026.
ABSTRACT Living with a chronic health condition (CHC) can involve sustained exposure to uncertainty, bodily threat and disruption to identity, relationships and anticipated life trajectories. Although a substantial evidence base exists for psychological interventions in long‐term illness, theoretical accounts remain fragmented across modalities and ...
Liza Morton
wiley   +1 more source

Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana Gastrointestinal parasites were common in pigs sampled from Kpone Katamanso Municipality, Ghana, with an overall prevalence of 67.6%. Complementary formol–ether concentration, modified McMaster, and modified Ziehl–Neelsen techniques improved parasite detection, while polymerase chain reaction
Antoinette V. Keleve   +4 more
wiley   +1 more source

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