Results 41 to 50 of about 386,087 (352)

A 2-D guinea pig lung proteome map

Data in Brief, 2015
Guinea pigs represent an important model for a number of infectious and non-infectious pulmonary diseases. The guinea pig genome has recently been sequenced to full coverage, opening up new research avenues using genomics, transcriptomics and proteomics ...
Simone Schuller, Kjell Sergeant, Jenny Renaut, John. J. Callanan, Caitriona Scaife, Jarlath E. Nally   +5 more
doaj   +1 more source

ZOOMICS: Comparative Metabolomics of Red Blood Cells From Guinea Pigs, Humans, and Non-human Primates During Refrigerated Storage for Up to 42 Days

Frontiers in Physiology, 2022
Unlike other rodents, guinea pigs (Cavia porcellus) have evolutionarily lost their capacity to synthesize vitamin C (ascorbate) de novo and, like several non-human primates and humans, rely on dietary intake and glutathione-dependent recycling to cope ...
Lorenzo Bertolone, Hye Kyung H. Shin, Jin Hyen Baek, Yamei Gao, Steven L. Spitalnik, Paul W. Buehler, Paul W. Buehler, Angelo D’Alessandro, Angelo D’Alessandro   +8 more
doaj   +1 more source

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]

, 1987
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core  

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Upper-Room Ultraviolet Light and Negative Air Ionization to Prevent Tuberculosis Transmission [PDF]

, 2009
Background Institutional tuberculosis (TB) transmission is an important public health problem highlighted by the HIV/AIDS pandemic and the emergence of multidrug- and extensively drug-resistant TB.
A. Roderick Escombe, Alland, Altman, Armando Gonzalez, Arnold, Bailey Mitchell, Balasubramanian, Basu, Bock, Brubacher, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine Noakes, David A. J Moore, Dwyer, Eduardo Ticona, Escombe, Escombe, Escombe, First, First, First, Fletcher, Gandhi, Gast, Iseman, Jensen, Jon S Friedland, Joshi, Kerr, Ko, Ko, Macher, Marcos Navincopa, Menzies, Mitchell, Mitchell, Mohle-Boetani, Moore, Nardell, Nardell, Nardell, Nardell, Nicas, Noakes, Pai, Patricia Sheen, Peter Wilson, Richardson, Riley, Riley, Riley, Riley, Riley, Riley, Robert H Gilman, Rocio Ramirez, Rudnick, Seo, Stead, Talbot, Valway, Willi Quino, Xu, Xu   +65 more
core   +6 more sources

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Le cobaye Cavia porcellus L., comme animal de boucherie au Cameroun [PDF]

Tropicultura, 1994
Guinea Pig Cavia porcellus L. As A Meat Producing Animal In Cameroon. Guinea pig Cavia porcellus farming for meat production remains a marginalised activity in Cameroon in spite of the advantages this specie offers.
Ngou Ngoupayou, JD., Fotso, JM., Kouonmenioc, J.   +2 more
doaj  

Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]

, 1963
Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
core   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.

Journal of Lipid Research, 1990
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic acid (30 +/- 5%). All three bile acids became labeled to the same specific activity within 30 min after [3H]cholesterol was ...
GS Tint, GR Xu, AK Batta, S Shefer, W Niemann, G Salen   +5 more
doaj   +1 more source