Results 81 to 90 of about 831,459 (395)

POLIOMYELITIS IN GUINEA-PIGS [PDF]

JAMA: The Journal of the American Medical Association, 1913
P. H. Roemer 2 has noticed that guinea-pigs in his laboratory frequently died of a paralysis which was very similar to that of epidemic poliomyelitis. On studying the cause of this paralysis he found a non-bacterial, filterable virus which could be transmitted from guinea-pig to guinea-pig, and which caused, after an incubation period of nine to twelve
openaire   +2 more sources

New insights into the mechanisms and sites of action of lamotrigine [PDF]

, 2000
This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field excitatory postsynaptic potentials (fEPSP) and population spikes in the CA1 hippocampal region of guinea pigs.
Grunze, Heinz, Langosch, J. M., Walden, Jörg, Zhou, X. Y.   +3 more
core   +1 more source

Intratympanic dexamethasone microcrystals/lidocaine‐loaded PLGA non‐spherical microparticles for local drug delivery to the inner ear

Animal Models and Experimental Medicine, EarlyView.
Optimized lidocaine‐loaded PLGA non‐spherical particles (LPNMs) and dexamethasone microcrystals (DEX MCs) were prepared. They were then mixed in sodium hyaluronate solution to obtain a co‐delivery system, administrated in guinea pigs to evaluate the pharmacokinetics and biocompatibility of the system.
Dongcheng Wang, Xin Zhang, Zhen Wang, Cheng Ran, Jia Hao, Xiaobo Ma, Minghui Wang, Zhimin Zhou   +7 more
wiley   +1 more source

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

Advanced NanoBiomed Research, EarlyView.
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai, Bin Zhang, Hong Cheng, Yunzhu Huang, Xinyue Han, Yangnan Hu, Renjie Chai, Wei Cao   +7 more
wiley   +1 more source

. Preliminary data on nematode infections in guinea pigs in the province of Cajabamba (Cajamarca, Peru)

Bulgarian Journal of Veterinary Medicine
In the absence of local studies, the current study was conducted in four villages located in the province of Cajabamba (Cajamarca, Peru) to demonstrate and determine the point prevalence of enteric nematodes in guinea pigs (Cavia porcellus) raised in a ...
K. Tacilla, J. Rojas-Moncada, T. Torrel, W. Quispe , L. Vargas-Rocha   +4 more
doaj   +1 more source

Intranasal Mucosal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances the Protection of BCG-Primed Guinea Pigs against Pulmonary Tuberculosis

PLoS ONE, 2009
Background Recombinant adenovirus-vectored (Ad) tuberculosis (TB) vaccine platform has demonstrated great potential to be used either as a stand-alone or a boost vaccine in murine models.
Z. Xing, C. McFarland, J. Sallenave, A. Izzo, Jun Wang, D. Mcmurray   +5 more
semanticscholar   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Differences in Formation of Prepuce and Urethral Groove During Penile Development Between Guinea Pigs and Mice Are Controlled by Differential Expression of Shh, Fgf10 and Fgfr2

Cells
The penile tubular urethra forms by canalization of the urethral plate without forming an obvious urethral groove in mice, while the urethral epithelium forms a fully open urethral groove before urethra closure through the distal-opening-proximal-closing
Shanshan Wang, Zhengui Zheng
doaj   +1 more source

A comparative assessment of toxic effects of dimethylnitrosamine in six different species [PDF]

, 1980
The hepatotoxicity which usually accompanies the oral administration of dimethylnitrosamine (DMN) to laboratory animals was studied in male rats, guinea pigs, cats, lizards, ducks, and monkeys.
Bassir, Olumbe, Maduagwu, E. N.
core   +1 more source

Ontogeny of the malleus in Mesocricetus auratus (Mammalia, Rodentia): Systematic and functional implications for the muroid middle ear

The Anatomical Record, EarlyView.
Abstract The three mammalian auditory ossicles enhance sound transmission from the tympanic membrane to the inner ear. The anterior anchoring of the malleus is one of the key characters for functional classification of the auditory ossicles. Previous studies revealed a medial outgrowth of the mallear anterior process, the processus internus ...
Franziska Fritzsche, Wolfgang Maier, Irina Ruf   +2 more
wiley   +1 more source