Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie +12 more
wiley +1 more source
Establishment of an <i>Agrobacterium</i>-Mediated Transformation System for Blastospores of <i>Naematelia aurantialba</i>. [PDF]
Li R +6 more
europepmc +1 more source
Objectives The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in non‐lymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Mutations in Components of the TREX-2 Complex Result in Misexpression of the Kelch-Domain F-Box Protein KFB39 Promoter in <i>Arabidopsis thaliana</i>. [PDF]
Matthes MC +3 more
europepmc +1 more source
Adaptive mixing formation control of multiquadrotor unmanned aerial vehicle systems
Abstract This paper presents a distributed adaptive mixing control (AMC) design for formation maintenance of systems of multiquadrotor UAVs (q‐UAVs) during commanded path‐tracking maneuvers. The proposed formation control scheme has a two‐level structure. The high level defines the desired trajectories for rigid and persistent formation acquisition and
Nasrettin Köksal +2 more
wiley +1 more source
Calmodulin-dependent protein kinase-related kinase CRK5 contributes to the regulation of the PIN3 cellular localization domain upon plant weight increase. [PDF]
Brunot-Garau P +2 more
europepmc +1 more source
Repeating Nuclear Transients From Repeating Partial Tidal Disruption Events
ABSTRACT Extragalactic nuclear transients that exhibit repeating outbursts can be modeled as the repeated dynamical interaction between bound stars and supermassive black holes (SMBHs). A subset of these transients, with recurrence timescales of months‐to‐years, have been explained as accretion flares from the repeated tidal stripping of a star by an ...
Ananya Bandopadhyay +4 more
wiley +1 more source
Agrivax: A chemical inducer of plant immunity identified by high-throughput screening. [PDF]
Liu C, Shi Q, Bai N, Hu X, Ye Y, Zhou L.
europepmc +1 more source
The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth +7 more
wiley +1 more source
The YPEL gene <i>CELL DIVISION SUPPRESSOR</i> negatively regulates cell division in plants. [PDF]
Hsu WH, Chao ZS, Kuo CW, Li YC, Yang CH.
europepmc +1 more source

