Results 21 to 30 of about 62,774 (121)

The microbiota-gut-brain axis: clinical applications in obesity and type 2 diabetes

Revista de Investigación Clínica, 2022
Recent investigations highlight the importance of the gut microbiota and bacteria-derived metabolites as key components in obesity and metabolic health. The microbiota-gut-brain axis presents promising targets for future obesity treatments and prevention.
Brandy Moser, Megan A. Milligan, Maria C. Dao   +2 more
doaj   +1 more source

Microbiota-gut-brain axis and nutritional strategy under heat stress

Animal Nutrition, 2021
Heat stress is a very universal stress event in recent years. Various lines of evidence in the past literatures indicate that gut microbiota composition is susceptible to variable temperature.
Chaoyue Wen, Siyu Wei, Xin Zong, Yizhen Wang, Mingliang Jin   +4 more
doaj   +1 more source

Sex-dependent effects of a high-fat diet on the hypothalamic response in mice

Biology of Sex Differences
Sex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux, Candice Lefebvre, Charles-Edward Breemeersch, Colin Salaün, Christine Bôle-Feysot, Charlène Guérin, Pierre Déchelotte, Alexis Goichon, Moïse Coëffier, Ludovic Langlois   +9 more
doaj   +1 more source

Intestinal epithelial TLR4 knock out induces sex-specific effects on gut barrier and microbiome in an activity-based anorexia model

Gut Microbes
The role of the microbiota‒gut‒brain axis in the pathophysiology of anorexia nervosa has emerged in recent decades. Increased expression of Toll-like receptor 4 (TLR4) has been reported in the intestinal epithelial cells (IEC) of activity-based anorexia (
Colin Salaün, Marion Huré, Charlène Guérin, Christine Bôle-Feysot, Audrey Valentin, Fatima Léon, Sarah Lenoir, Jean-Luc do-Rego, Jean-Claude do-Rego, Ludovic Langlois, David Ribet, Najate Achamrah, Moïse Coëffier   +12 more
doaj   +1 more source

The gut-brain axis in ischemic stroke: its relevance in pathology and as a therapeutic target

Neurological Research and Practice, 2022
The gut contains the largest reservoir of microorganisms of the human body, termed as the gut microbiota which emerges as a key pathophysiological factor in health and disease. The gut microbiota has been demonstrated to influence various brain functions
Corinne Benakis, Arthur Liesz
doaj   +1 more source

Epidemiology and risk factors of Alzheimer’s disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis protocol

BMJ Open
Background Alzheimer’s disease (AD) impacts over 55 million individuals worldwide and remains the leading cause of dementia (60–70% of cases). By 2050, South and Southeast Asia are projected to have an older adult population more than double, bearing a ...
Zhahirul Islam, Israt Jahan, Sharmin Sultana, Nowshin Papri, Mantaka Rahman, Imran Hasan, Tamal Saha, Shoma Hayat, Ashiqa Tabassum, Md Abu Jaher Nayeem   +9 more
doaj   +1 more source

Interleukin‐10 promoter polymorphisms and haplotypes in patients with Guillain–Barré syndrome

Annals of Clinical and Translational Neurology
Objective Interleukin‐10 (IL‐10) is a multifunctional cytokine that exerts both pro‐ and anti‐inflammatory effects on the immune system as well as in the pathogenesis of Guillain–Barré syndrome (GBS).
Shoma Hayat, Asaduzzaman Asad, Moriam Akter Munni, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Israt Jahan, Md. Zakir Hossain Howlader, Quazi Deen Mohammad, Zhahirul Islam   +8 more
doaj   +1 more source

Brain-gut axis: From the conditioned reflex to the microbiota-gut-brain communication system

Интегративная физиология, 2020
Communication between the central nervous system (CNS) and the gastrointestinal tract is called the brain-gut axis. This communication network includes the CNS, hypothalamic-pituitary-adrenal axis, the autonomic nervous system (sympathetic and ...
Klara Gyires
doaj   +1 more source

Shedding light on biological sex differences and microbiota–gut–brain axis: a comprehensive review of its roles in neuropsychiatric disorders

Biology of Sex Differences, 2022
Highlights The human microbiome is a unique set of organisms affecting health via the gut–brain axis. Neuropsychiatric disorders, eating disorders, neurodevelopmental disorders, and neurodegenerative disorders are regulated by the microbiota–gut–brain ...
Parnian Shobeiri, Amirali Kalantari, Antônio L. Teixeira, Nima Rezaei   +3 more
doaj   +1 more source

Sex-dependent circadian alterations of both central and peripheral clock genes expression and gut–microbiota composition during activity-based anorexia in mice

Biology of Sex Differences
Rationale Patients with anorexia nervosa (AN) often present sleep disorders and circadian hormonal dysregulation. The role of the microbiota–gut–brain axis in the regulation of feeding behavior has emerged during the last decades but its relationships ...
Colin Salaün, Marine Courvalet, Léna Rousseau, Kévin Cailleux, Jonathan Breton, Christine Bôle-Feysot, Charlène Guérin, Marion Huré, Alexis Goichon, Jean-Claude do Rego, Pierre Déchelotte, David Ribet, Najate Achamrah, Moïse Coëffier   +13 more
doaj   +1 more source