Results 11 to 20 of about 1,632,982 (236)

Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy [PDF]

open access: yesFrontiers in Medicine
IntroductionGrowing evidence suggests that gut microbiota may influence renal function via the gut–kidney axis. This study assessed gut microbial composition, metabolic indicators, and inflammatory markers in elderly individuals with varying degrees of ...
Ziyi Li   +12 more
doaj   +4 more sources

An Overview of Chronic Kidney Disease Pathophysiology: The Impact of Gut Dysbiosis and Oral Disease [PDF]

open access: yesBiomedicines, 2023
Chronic kidney disease (CKD) is a severe condition and a significant public health issue worldwide, carrying the burden of an increased risk of cardiovascular events and mortality. The traditional factors that promote the onset and progression of CKD are
Serena Altamura   +4 more
doaj   +3 more sources

Gut–Kidney Axis Investigations in Animal Models of Chronic Kidney Disease

open access: yesToxins, 2022
Chronic kidney disease (CKD) is an incurable disease in which renal function gradually declines, resulting in no noticeable symptoms during the early stages and a life-threatening disorder in the latest stage. The changes that accompany renal failure are
Piotr Bartochowski   +6 more
doaj   +2 more sources

The Links between Microbiome and Uremic Toxins in Acute Kidney Injury: Beyond Gut Feeling—A Systematic Review

open access: yesToxins, 2020
The last years have brought an abundance of data on the existence of a gut-kidney axis and the importance of microbiome in kidney injury. Data on kidney-gut crosstalk suggest the possibility that microbiota alter renal inflammation; we therefore aimed to
Alicja Rydzewska-Rosołowska   +5 more
doaj   +2 more sources

Gut microbiota–derived short-chain fatty acids and kidney diseases

open access: yesDrug Design, Development and Therapy, 2017
Lingzhi Li, Liang Ma, Ping Fu Kidney Research Institute, Department of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, China Abstract: Gut microbiota and its metabolites play pivotal roles in host physiology and pathology.
Li L, Ma L, Fu P
doaj   +1 more source

The Kidney–Gut Axis as a Novel Target for Nutritional Intervention to Counteract Chronic Kidney Disease Progression

open access: yesMetabolites
A well-balanced diet is integral for overall health, aiding in managing key risk factors for kidney damage like hypertension while supplying necessary precursors for metabolite production.
Sandra Cabała   +2 more
doaj   +2 more sources

Role of the Gut Microbiota in Children with Kidney Disease

open access: yesChildren, 2023
Disruption of the composition and structure of the gut microbiota, namely dysbiosis, dictates the pathophysiology of kidney diseases. The bidirectional kidney–gut axis is of interest in chronic kidney disease (CKD); the uremic milieu leads to intestinal ...
You-Lin Tain, Chien-Ning Hsu
doaj   +2 more sources

The gut–kidney axis in high-altitude hypoxia: pathophysiological mechanisms and the central role of hypoxia inducible factor [PDF]

open access: yesAnnals of Medicine
Background The high-altitude plateau environment, defined by hypobaric hypoxia, poses considerable health risks to human populations. Due to their substantial oxygen requirements, the kidneys are particularly susceptible, as are the intestines, with ...
Peiwen Wu   +6 more
doaj   +2 more sources

A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases [PDF]

open access: yesNature Communications
Cardiovascular diseases (CVD) remain a major global health challenge. Early markers of disease initiation and progression are urgently needed. We, and others, have previously shown changes in the gut microbiome in association with metabolic and CVD. Here,
Kanta Chechi   +74 more
doaj   +3 more sources

Exploring the Role of Microbiota-mediated Gut-Kidney Axis in Acute Kidney Injury: Immunomodulation & Therapy [PDF]

open access: yesKidney Diseases
Background: Acute kidney injury (AKI) remains a major clinical problem characterized by high morbidity and an increased risk of progression to chronic kidney disease (CKD). Immune cell infiltration and activation are important features of AKI;
Litong Zhu   +6 more
doaj   +2 more sources

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