Results 41 to 50 of about 155,705 (354)

Gut/brain axis and the microbiota [PDF]

Journal of Clinical Investigation, 2015
Tremendous progress has been made in characterizing the bidirectional interactions between the central nervous system, the enteric nervous system, and the gastrointestinal tract. A series of provocative preclinical studies have suggested a prominent role for the gut microbiota in these gut-brain interactions.
Mayer, Emeran A, Tillisch, Kirsten, Gupta, Arpana   +2 more
openaire   +4 more sources

Pain determinants and quality of life in Guillain-Barre syndrome: a prospective cohort study

BMJ Neurology Open
Background Pain is a serious manifestation in both the acute and chronic stages of Guillain-Barre syndrome (GBS). We evaluated the frequency, characteristics and associated factors of pain and its impact on quality of life (QoL) among patients with GBS ...
Badrul Islam, Zhahirul Islam, Israt Jahan, Gulshan Ara, Nowshin Papri, Asif Mohammed, Md. Mantaka Rahman, Imran Hasan, Rufydha Azam, Tamal Saha, Farzana Tamanna Ummey Shaon, Shoma Hayat   +11 more
doaj   +1 more source

Association Among Gut Microbes, Intestinal Physiology, and Autism [PDF]

, 2017
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by two core symptoms: social deficits and increase in stereotypic/repetitive behaviors.
Wu, Wei-Li
core   +3 more sources

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

Hypothesis and theory : a pathophysiological concept of stroke-induced acute phase response and increased intestinal permeability leading to secondary brain damage [PDF]

, 2020
Gut integrity impairment leading to increased intestinal permeability (IP) is hypothesized to be a trigger of critically illness. Approximately 15–20% of human ischemic stroke (IS) victims require intensive care, including patients with impaired level of
Barthel, Henryk, Boltze, Johannes, Dreyer, Antje Y., Ferrara, Fabienne, McLeod, Damian D., Nitzsche, Björn, Pieper, Laura, Pietsch, Sören, Rütten, Rita, Schatzl, Ann-Kathrin, Schrödl, Wieland, Zeisig, Vilia   +11 more
core   +1 more source

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

International Journal of Infectious Diseases
Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C.
Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam   +7 more
doaj   +1 more source

Gut microbiota, metabolism and psychopathology:A critical review and novel perspectives [PDF]

, 2018
Psychiatric disorders are often associated with metabolic comorbidities. However, the mechanisms through which metabolic and psychiatric disorders are connected remain unclear.
de Clercq, Nicolien C, Groen, Albert K, Groen, Robin N, Hoenders, H J Rogier, Nieuwdorp, Max   +4 more
core   +2 more sources

Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients

Microbiology Spectrum
Multi-drug resistance (MDR) in Shigella continues to pose a significant public health challenge, particularly in developing countries. Recent advances in genomics strengthen the surveillance of MDR-pathogens and antimicrobial resistance (AMR) mediators ...
Asaduzzaman Asad, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Ruma Begum, Shah Nayeem Faruque, Suraia Nusrin, Israt Jahan, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

Gut-brain axis: Role of lipids in the regulation of inflammation, pain and CNS diseases [PDF]

, 2018
The human gut is a composite anaerobic environment with a large, diverse and dynamic enteric microbiota, represented by more than 100 trillion microorganisms, including at least 1000 distinct species.
Avagliano, Carmen, BERNI CANANI, Roberto, Calignano, Antonio, Cristiano, Claudia, DE CARO, Carmen, LA RANA, Giovanna, MATTACE RASO, Giuseppina, Meli, Rosaria, Russo, Roberto   +8 more
core   +1 more source

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Nature Communications, 2019
Early life stress has been associated with the occurrence of gastrointestinal diseases later in life, but underlying mechanisms remain poorly understood. Here, Wong et al.
Hoi Leong Xavier Wong, Hong-yan Qin, Siu Wai Tsang, Xiao Zuo, Sijia Che, Chi Fung Willis Chow, Xi Li, Hai-tao Xiao, Ling Zhao, Tao Huang, Cheng Yuan Lin, Hiu Yee Kwan, Tao Yang, Frank M. Longo, Aiping Lyu, Zhao-xiang Bian   +15 more
doaj   +1 more source