Results 91 to 100 of about 1,633,030 (251)
, 2020 Gut microbiota play an important role in maintaining intestinal health and are involved in the metabolism of carbohydrates, lipids, and amino acids. Recent studies have shown that the central nervous system (CNS) and enteric nervous system (ENS) can ...
Adeli, Khosrow +5 more
core +1 more source
Advanced Science, EarlyView.Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi +8 more
wiley +1 more source
Promise of Synbiotic in Gut-Kidney Axis
Cermin Dunia KedokteranHuman microbiota plays a role in protecting human health. Change in the microbial composition will lead to an imbalance between the beneficial and potentially harmful bacteria, leading to “dysbiosis”. The pathogenic interconnection between gut microbiota and kidney diseases is called the gut–kidney axis, which is implicated in a wide range of clinical ...
openaire +1 more source
Gut Microbiota in Chronic Kidney Disease: A Narrative Literature Review [PDF]
Chronic kidney disease (CKD) is a growing public health problem related to loss of kidney function and cardiovascular disease as the main causes of morbidity and mortality in CKD. It is known that CKD is associated with intestinal dysbiosis.
Zulklhair Ali +6 more
core +1 more source
Gut dysbiosis and the role of probiotics in chronic kidney disease
, 2023 Chronic inflammatory condition in chronic kidney disease (CKD) patients is associated with increased risk of cardiovascular morbidity and mortality. Gut dysbiosis is assumed as one of leading factors to the chronic inflammatory condition.
Cahyadi, Alius +3 more
core +2 more sources
BMC MicrobiologyHigh-salt diet (HSD) is a major risk factor for renal injury, and gut microbiota may play a role in this process. In this study, we investigated the potential role of gut microbiota in HSD-related renal injury and the microbial mechanisms involved ...
Tian-hao Liu +10 more
doaj +1 more source
Advanced Science, EarlyView.Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath +9 more
wiley +1 more source
Frontiers in PharmacologyBackgroundDiabetic nephropathy (DN) is a severe complication of diabetes, which has been increasingly associated with gut microbiota dysbiosis and inflammatory dysregulation.ObjectiveThis study investigates the dual therapeutic potential of diosgenin ...
Jiang Shanshan +8 more
doaj +1 more source
Advanced Science, EarlyView.Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu +6 more
wiley +1 more source
Gut Microbiome and Kidney Disease in Pediatrics: Does Connection Exist? [PDF]
, 2016 Child development is a unique and continuous process that is impacted by genetics and environmental factors. Gut microbiome changes with development and depends on the stage of gut maturation, nutrition, and overall health.
Tetyana L. Vasylyeva +2 more
core +1 more source