Results 81 to 90 of about 2,005,973 (405)
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Pain determinants and quality of life in Guillain-Barre syndrome: a prospective cohort study
Background Pain is a serious manifestation in both the acute and chronic stages of Guillain-Barre syndrome (GBS). We evaluated the frequency, characteristics and associated factors of pain and its impact on quality of life (QoL) among patients with GBS ...
Badrul Islam+11 more
doaj +1 more source
Gut microbiota in HIV-pneumonia patients is related to peripheral CD4 counts, lung microbiota, and in vitro macrophage dysfunction. [PDF]
Pneumonia is common and frequently fatal in HIV-infected patients, due to rampant, systemic inflammation and failure to control microbial infection. While airway microbiota composition is related to local inflammatory response, gut microbiota has been ...
Byanyima, Patrick+14 more
core +2 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Microbiome-gut-brain axis and toll-like receptors in parkinson\u2019s disease [PDF]
Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy, which involves all districts of the brain-gut axis, including the central, autonomic and enteric nervous systems.
Caputi, Valentina, Giron, Maria Cecilia
core +2 more sources
Probing the Supersymmetric Grand Unified Theories at the Future Proton-Proton Colliders and Hyper-Kamiokande Experiment [PDF]
Gauge coupling unification in the Supersymmetric Standard Models strongly implies the Grand Unified Theories (GUTs). With the grand desert hypothesis, we show that the supersymmetric GUTs can be probed at the future proton-proton (pp) colliders and Hyper-Kamiokande experiment.
arxiv +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
A note on compact and compact circular edge-colorings of graphs [PDF]
Graphs and ...
Dariusz Dereniowski, Adam Nadolski
doaj +1 more source