The Microbiota-Gut-Brain Axis.
Physiological Reviews, 2019 The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota (the trillions of microorganisms within and on our bodies) as one of the key regulators of gut ...
J. Cryan +32 more
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Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature [PDF]
, 2016 The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors); however none of these fully explain the increase in the prevalence of obesity worldwide.
Edwards, Christine Ann +3 more
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2'-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice. [PDF]
, 2020 Obesity is characterized by fat accumulation, chronic inflammation and impaired satiety signaling, which may be due in part to gut microbial dysbiosis. Manipulations of the gut microbiota and its metabolites are attractive targets for obesity treatment ...
Barile, Daniela +5 more
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TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]
, 2019 The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen +5 more
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Gut-Microbiota-Derived Metabolites Maintain Gut and Systemic Immune Homeostasis
Cells, 2023 The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the gastrointestinal tract. This commensal microbiota can contribute to the regulation of host immune response and homeostasis.
Juanjuan Wang +4 more
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Analysis of gut microbiota in rheumatoid arthritis patients. Disease-related dysbiosis and modifications induced by etanercept [PDF]
, 2018 A certain number of studies were carried out to address the question of how dysbiosis could affect the onset and development of rheumatoid arthritis (RA), but little is known about the reciprocal influence between microbiota composition and ...
D'Amelio, R +11 more
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Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling
mSystems, 2019 Proper preservation of stool samples to minimize microbial community shifts and inactivate infectious agents is important for self-collected specimens requiring shipment to laboratories when cold chain transport is not feasible.
Zigui Chen +9 more
doaj +3 more sources
The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]
, 2018 BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X +7 more
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Microorganisms, 2022 Obesity, a worldwide health concern with a constantly rising prevalence, is a multifactorial chronic disease associated with a wide range of physiological disruptions, including energy imbalance, central appetite and food reward dysregulation, and ...
Jonathan Breton +2 more
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Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications
Signal Transduction and Targeted Therapy, 2023 In the past period, due to the rapid development of next-generation sequencing technology, accumulating evidence has clarified the complex role of the human microbiota in the development of cancer and the therapeutic response. More importantly, available
Lin-yong Zhao +9 more
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