Results 51 to 60 of about 223,316 (222)

Information content of high-order associations of the human gut microbiota network [PDF]

arXiv, 2020
The human gastrointestinal tract is an environment that hosts an ecosystem of microorganisms essential to human health. Vital biological processes emerge from fundamental inter- and intra-species molecular interactions that influence the assembly and composition of the gut microbiota ecology.
arxiv  

Network analysis of a complex disease: the gut microbiota in the inflammatory bowel disease case [PDF]

arXiv, 2022
Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class of diseases makes them suitable to be represented and studied with network science.
arxiv  

Gut microbiota and aging.

European review for medical and pharmacological sciences, 2018
The hypothesis of an important role of gut microbiota in maintaining physiological state into the gastrointestinal (GI) system is supported by qualitative and quantitative alteration of the intestinal flora in a number of physiological and pathological condition as shown in several studies. The evidence of the inflammatory state alteration, highlighted
Mangiola, F, Nicoletti, A, Gasbarrini, A, Ponziani, F R   +3 more
openaire   +4 more sources

Lipid droplet formation induced by icaritin derivative IC2 promotes a combination strategy for cancer therapy

Chinese Medicine
Background Lipid metabolism is crucial in cancer progression. Lipid droplets (LDs) generated in cancer cells can act as protective mechanisms through alleviating lipotoxicity under stress conditions.
Guosheng Wu, Liang Ying, Qian Zhang, He Xiong, Jie Wang, Sitao Chen, Chen Yang, Yiyuan Jin, Zengwei Lai, Ninghan Feng, Yunjun Ge   +10 more
doaj   +1 more source

Comprehensive analysis of stearoyl-coenzyme A desaturase in prostate adenocarcinoma: insights into gene expression, immune microenvironment and tumor progression

Frontiers in Immunology
Prostate adenocarcinoma (PRAD) is a prevalent global malignancy which depends more on lipid metabolism for tumor progression compared to other cancer types.
Jie Wang, Liang Ying, He Xiong, Duan-Rui Zhou, Yi-Xuan Wang, Hui-Lian Che, Zhang-Feng Zhong, Guo-Sheng Wu, Yun-Jun Ge   +8 more
doaj   +1 more source

Bifidobacterium infantis Maintains Genome Stability in Ulcerative Colitis via Regulating Anaphase-Promoting Complex Subunit 7

Frontiers in Microbiology, 2021
Probiotics represents a promising intestinal microbiota-targeted therapeutic method for the treatment of ulcerative colitis (UC). Several lines of evidence implicate that Bifidobacterium infantis serves as a probiotic strain with proven efficacy in ...
Taotao Han, Taotao Han, Xiaomin Hu, Xiaomin Hu, Kemin Li, Kemin Li, Di Zhang, Di Zhang, Yan Zhang, Jingnan Li, Jingnan Li   +10 more
doaj   +1 more source

Association between the atherogenic index of plasma and new-onset non-alcoholic fatty liver disease in non-obese participants

Frontiers in Endocrinology, 2022
IntroductionNon-alcoholic fatty liver disease (NAFLD) in the non-obese population accounts for a large proportion of NAFLD. Atherogenic index of plasma (AIP, defined as the logarithm of the triglyceride/high-density lipoprotein cholesterol ratio.) can ...
Kemin Li, Kemin Li, Ji Li, Ji Li, Xiaoyun Cheng, Xiaoyun Cheng, Jing Wang, Jing Wang, Jingnan Li, Jingnan Li   +9 more
doaj   +1 more source

Gut microbiota and autism

Journal of Education, Health and Sport, 2019
Boreński Grzegorz, Wójcik Magdalena, Poleszak Julita, Szabat Przemysław, Szabat Marta, Milanowska Joanna. Gut microbiota and autism. Journal of Education, Health and Sport. 2019;9(9):204-212. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3395320 http://ojs.ukw.edu.pl/index.php/johs/article/view/7380 The journal has had 5 points in Ministry of ...
Grzegorz Boreński, Magdalena Wójcik, Julita Poleszak, Przemysław Szabat, Marta Szabat, Joanna Milanowska   +5 more
openaire   +3 more sources

Nuclease-Treated Stabilized Fermentation Product of Cetobacterium somerae Improves Growth, Non-specific Immunity, and Liver Health of Zebrafish (Danio rerio)

Frontiers in Nutrition, 2022
High-fat diets (HFD) are harmful to fish health. Probiotics are commonly utilized to improve fish nutrition metabolism, immune response, and health. Nucleic acids of the probiotic bacterium can be hydrolyzed by nuclease to generate nucleotides.
Mingxu Xie, Mingxu Xie, Qiang Hao, Qiang Hao, Rui Xia, Rolf Erik Olsen, Einar Ringø, Yalin Yang, Zhen Zhang, Chao Ran, Zhigang Zhou   +10 more
doaj   +1 more source

Annonaceous acetogenins mimic AA005 targets mitochondrial trifunctional enzyme alpha subunit to treat obesity in male mice

Nature Communications
Obesity and related diseases pose a major health risk, yet current anti-obesity drugs inadequately addressing clinical needs. Here we show AA005, an annonaceous acetogenin mimic, resists obesity induced by high-fat diets and leptin mutations at non-toxic
Bing Han, Zhan-Ming Li, Xu-Yun Zhao, Kai Liang, Yu-Qin Mao, Shi-Long Zhang, Li-Ying Huang, Chao-Yue Kong, Xin Peng, Hui-Ling Chen, Jia-Ting Huang, Zhao-Xia Wu, Jin-Qing Yao, Pei-Ran Cai, Zheng-Yan Zhang, Xu-Min Zhang, Zhu-Jun Yao, Guo-Qiang Chen, Li-Shun Wang   +18 more
doaj   +1 more source